Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1937776..1938366 Replicon chromosome
Accession NZ_CP099377
Organism Citrobacter braakii strain RHB23-SO-C01

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag NFK19_RS09135 Protein ID WP_049041157.1
Coordinates 1938034..1938366 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag NFK19_RS09130 Protein ID WP_049041154.1
Coordinates 1937776..1938033 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK19_RS09125 (1933265) 1933265..1937164 - 3900 WP_279266947.1 hypothetical protein -
NFK19_RS09130 (1937776) 1937776..1938033 + 258 WP_049041154.1 antitoxin Antitoxin
NFK19_RS09135 (1938034) 1938034..1938366 + 333 WP_049041157.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NFK19_RS09145 (1938614) 1938614..1940101 - 1488 WP_049040618.1 EmmdR/YeeO family multidrug/toxin efflux MATE transporter -
NFK19_RS09155 (1940499) 1940499..1941761 + 1263 WP_181545753.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11731.54 Da        Isoelectric Point: 8.5572

>T248730 WP_049041157.1 NZ_CP099377:1938034-1938366 [Citrobacter braakii]
MDRGEIWLVSLDPTAGHEQSGKRPVLIVSPASFNKFTRLPVVVPVTSGGNFARAAGFTVSLDGVGTKTTGVIRCDQPRTI
DMGARNGKCLERIPEAVVNEVLARLEAILS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9370.85 Da        Isoelectric Point: 4.4354

>AT248730 WP_049041154.1 NZ_CP099377:1937776-1938033 [Citrobacter braakii]
MYTTRLKKVGGSIMLAVPPAVLKTLALSTDSEVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSDEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References