Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 659158..659734 Replicon chromosome
Accession NZ_CP099376
Organism Citrobacter braakii strain RHB23-SO-C04

Toxin (Protein)


Gene name shpA Uniprot ID A0A7L6U8Z2
Locus tag NFK21_RS03210 Protein ID WP_049040418.1
Coordinates 659158..659445 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag NFK21_RS03215 Protein ID WP_047414530.1
Coordinates 659432..659734 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK21_RS03200 (655233) 655233..657662 - 2430 WP_279266796.1 DEAD/DEAH box helicase family protein -
NFK21_RS03205 (657758) 657758..658924 - 1167 WP_019078303.1 restriction endonuclease -
NFK21_RS03210 (659158) 659158..659445 + 288 WP_049040418.1 BrnT family toxin Toxin
NFK21_RS03215 (659432) 659432..659734 + 303 WP_047414530.1 BrnA antitoxin family protein Antitoxin
NFK21_RS03220 (660042) 660042..661889 - 1848 WP_137380245.1 NERD domain-containing protein/DEAD/DEAH box helicase -
NFK21_RS03225 (662076) 662076..663032 - 957 WP_016155616.1 GTPase -
NFK21_RS03230 (663045) 663045..663239 - 195 WP_003830038.1 YbdD/YjiX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(46-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11293.68 Da        Isoelectric Point: 7.5237

>T248716 WP_049040418.1 NZ_CP099376:659158-659445 [Citrobacter braakii]
MPMEFEWDANKAQSNHRKHGVRFEDAILVFDDPQHLSRQDRYENGEYRWQTIGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADRKERSRYEHS

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11476.08 Da        Isoelectric Point: 9.5650

>AT248716 WP_047414530.1 NZ_CP099376:659432-659734 [Citrobacter braakii]
MSIVKHKRGSVSALSAQHEAELKALANKPDDDIDYSDIPVTEDELWSEAHRGKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7L6U8Z2

Antitoxin

Source ID Structure

References