Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 4340728..4341431 Replicon chromosome
Accession NZ_CP099375
Organism Citrobacter braakii strain RHB25-E4-C05

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag NFK28_RS20910 Protein ID WP_166465229.1
Coordinates 4340728..4341069 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NFK28_RS20915 Protein ID WP_166465230.1
Coordinates 4341090..4341431 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK28_RS20880 (4336452) 4336452..4336814 + 363 WP_019078284.1 endoribonuclease SymE -
NFK28_RS20885 (4336877) 4336877..4337362 - 486 WP_016151545.1 type VI secretion system tube protein TssD -
NFK28_RS20890 (4337381) 4337381..4337707 - 327 WP_016155588.1 DUF1493 family protein -
NFK28_RS20895 (4337701) 4337701..4338150 - 450 WP_003830103.1 hypothetical protein -
NFK28_RS20900 (4338409) 4338409..4339281 + 873 WP_081000487.1 HNH endonuclease -
NFK28_RS20905 (4339462) 4339462..4340469 - 1008 WP_127675147.1 restriction endonuclease -
NFK28_RS20910 (4340728) 4340728..4341069 - 342 WP_166465229.1 TA system toxin CbtA family protein Toxin
NFK28_RS20915 (4341090) 4341090..4341431 - 342 WP_166465230.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFK28_RS20920 (4341442) 4341442..4341984 - 543 WP_166465231.1 DNA repair protein RadC -
NFK28_RS20925 (4341997) 4341997..4342440 - 444 WP_047365977.1 antirestriction protein -
NFK28_RS20930 (4342471) 4342471..4343292 - 822 WP_166465232.1 DUF932 domain-containing protein -
NFK28_RS20935 (4343377) 4343377..4343892 - 516 WP_166465233.1 DUF4234 domain-containing protein -
NFK28_RS20940 (4343954) 4343954..4344421 - 468 WP_166465234.1 hypothetical protein -
NFK28_RS20945 (4344517) 4344517..4344918 - 402 WP_166465235.1 hypothetical protein -
NFK28_RS20950 (4345121) 4345121..4346008 - 888 WP_166465236.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4337701..4350604 12903


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(13-111)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12633.59 Da        Isoelectric Point: 5.6618

>T248713 WP_166465229.1 NZ_CP099375:c4341069-4340728 [Citrobacter braakii]
MKTLPATTPQAATLCLSPVAVWQMLLACLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNLLVEKYELVRIDRRGF
NWQEQSPYLRAVDILRARQATGLLKINRISAAQ

Download         Length: 342 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12808.28 Da        Isoelectric Point: 6.2098

>AT248713 WP_166465230.1 NZ_CP099375:c4341431-4341090 [Citrobacter braakii]
MKSTDSENDSFLKWGLNRNVTPFFGARLIQEGNRLHYLADRASISGEFSNAESLKLDEVFPHFISQMESMLTTGEMNPRH
AHGVTLYHNGFTCEADTLGSYGYVYIAVYPTHR

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References