248702

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 840034..840819 Replicon chromosome
Accession NZ_CP099375
Organism Citrobacter braakii strain RHB25-E4-C05

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NFK28_RS04125 Protein ID WP_040063377.1
Coordinates 840034..840411 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFK28_RS04130 Protein ID WP_038633768.1
Coordinates 840460..840819 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK28_RS04095 (835388) 835388..835855 - 468 WP_047358704.1 DUF6392 family protein -
NFK28_RS04100 (835855) 835855..836430 - 576 WP_081000505.1 S-type pyocin domain-containing protein -
NFK28_RS04105 (836391) 836391..837632 - 1242 WP_053390097.1 S-type pyocin domain-containing protein -
NFK28_RS04110 (838393) 838393..839241 - 849 WP_040229927.1 DUF4942 domain-containing protein -
NFK28_RS04115 (839322) 839322..839516 - 195 WP_047661001.1 DUF957 domain-containing protein -
NFK28_RS04120 (839546) 839546..840037 - 492 WP_040063379.1 DUF5983 family protein -
NFK28_RS04125 (840034) 840034..840411 - 378 WP_040063377.1 TA system toxin CbtA family protein Toxin
NFK28_RS04130 (840460) 840460..840819 - 360 WP_038633768.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFK28_RS04135 (840842) 840842..841063 - 222 WP_038633763.1 DUF987 domain-containing protein -
NFK28_RS04140 (841075) 841075..841560 - 486 WP_038642868.1 DNA repair protein RadC -
NFK28_RS04145 (841613) 841613..842008 - 396 WP_052322945.1 antirestriction protein -
NFK28_RS04150 (842086) 842086..842349 - 264 WP_038633754.1 hypothetical protein -
NFK28_RS04155 (842349) 842349..843167 - 819 WP_001234374.1 DUF932 domain-containing protein -
NFK28_RS04160 (843283) 843283..843533 - 251 Protein_818 DUF905 family protein -
NFK28_RS04165 (843724) 843724..844191 - 468 WP_000727137.1 hypothetical protein -
NFK28_RS04170 (844288) 844288..844689 - 402 WP_047660999.1 hypothetical protein -
NFK28_RS04175 (844895) 844895..845782 - 888 WP_047661008.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 807028..855396 48368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14020.87 Da        Isoelectric Point: 6.8604

>T248702 WP_040063377.1 NZ_CP099375:c840411-840034 [Citrobacter braakii]
MQTQPVSPAREASPRLSPVEIWQRLLSHLLDHHYGLALNDTPFGNDDVIQEHIDAGISLCDAVNFIVEKYDLVRTDRYGS
STTEQSPLISSIDILRARKACGLMTRNGYRAVTDITTGKYSKMTR

Download         Length: 378 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13318.30 Da        Isoelectric Point: 7.4424

>AT248702 WP_038633768.1 NZ_CP099375:c840819-840460 [Citrobacter braakii]
MLNKTLPANHHISEPWWGLKRNITPCFGARLVQEGNRLHYLADRASITGTFTDADLRHLDQAFPVLLKQMELMLVSGELS
PRHQHCVTLYAKGLTCEADSLGSHGYIYIAIYPTPSVTS

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References