Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4400205..4400724 Replicon chromosome
Accession NZ_CP099374
Organism Citrobacter braakii strain RHB25-SO-C06

Toxin (Protein)


Gene name relE Uniprot ID A0A8I0G602
Locus tag NFK30_RS21175 Protein ID WP_047414720.1
Coordinates 4400205..4400486 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0V9JX71
Locus tag NFK30_RS21180 Protein ID WP_016155558.1
Coordinates 4400476..4400724 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK30_RS21160 (4397210) 4397210..4397674 + 465 WP_016155562.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFK30_RS21165 (4397693) 4397693..4398214 - 522 WP_109017767.1 hypothetical protein -
NFK30_RS21170 (4398214) 4398214..4400178 - 1965 WP_109017766.1 type VI secretion system tip protein TssI/VgrG -
NFK30_RS21175 (4400205) 4400205..4400486 - 282 WP_047414720.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFK30_RS21180 (4400476) 4400476..4400724 - 249 WP_016155558.1 hypothetical protein Antitoxin
NFK30_RS21185 (4400821) 4400821..4400949 - 129 WP_016155557.1 hypothetical protein -
NFK30_RS21190 (4401018) 4401018..4401491 - 474 WP_016155556.1 hypothetical protein -
NFK30_RS21195 (4401534) 4401534..4404035 - 2502 WP_109018352.1 type VI secretion system ATPase TssH -
NFK30_RS21200 (4404026) 4404026..4404973 - 948 WP_109018353.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10974.73 Da        Isoelectric Point: 10.4466

>T248700 WP_047414720.1 NZ_CP099374:c4400486-4400205 [Citrobacter braakii]
MTYNLEFLDVALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8987.28 Da        Isoelectric Point: 4.7513

>AT248700 WP_016155558.1 NZ_CP099374:c4400724-4400476 [Citrobacter braakii]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELAEDAELNRIADEREGGKRIKVSLN
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0V9JX71

References