Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 3012639..3013229 Replicon chromosome
Accession NZ_CP099374
Organism Citrobacter braakii strain RHB25-SO-C06

Toxin (Protein)


Gene name pemK Uniprot ID A0A8I0G229
Locus tag NFK30_RS14655 Protein ID WP_049270508.1
Coordinates 3012639..3012971 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID A0A8I0KQR6
Locus tag NFK30_RS14660 Protein ID WP_049270509.1
Coordinates 3012972..3013229 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK30_RS14630 (3007675) 3007675..3008034 - 360 WP_016156204.1 purine nucleoside phosphoramidase -
NFK30_RS14635 (3008383) 3008383..3010569 + 2187 WP_109017717.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
NFK30_RS14645 (3010904) 3010904..3012391 + 1488 WP_049040618.1 EmmdR/YeeO family multidrug/toxin efflux MATE transporter -
NFK30_RS14655 (3012639) 3012639..3012971 - 333 WP_049270508.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NFK30_RS14660 (3012972) 3012972..3013229 - 258 WP_049270509.1 antitoxin Antitoxin
NFK30_RS14665 (3013841) 3013841..3017740 + 3900 WP_109017714.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11784.58 Da        Isoelectric Point: 10.2965

>T248696 WP_049270508.1 NZ_CP099374:c3012971-3012639 [Citrobacter braakii]
MDRGEIWLVSLDPTAGHEQSGKRPVLIVSPASFNKFTRLPVVVPVTSGGNFARAAGFTVSLDGVGTKTTGVIRCDQPRTI
DMGARNGKRLERIPEAVVNEVLARLEAILS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9384.88 Da        Isoelectric Point: 4.4620

>AT248696 WP_049270509.1 NZ_CP099374:c3013229-3012972 [Citrobacter braakii]
MYTTRLKKVGGSVMLAVPPAVLKTLALSTDSEVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSEEEREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References