Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4817730..4818265 Replicon chromosome
Accession NZ_CP099373
Organism Citrobacter portucalensis strain RHB38-SO-C05

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFK58_RS23210 Protein ID WP_085049650.1
Coordinates 4817978..4818265 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D4BKM9
Locus tag NFK58_RS23205 Protein ID WP_006688247.1
Coordinates 4817730..4817981 (+) Length 84 a.a.

Genomic Context

NFK58_RS23175NFK58_RS23180NFK58_RS23185NFK58_RS23190NFK58_RS23195NFK58_RS23200NFK58_RS23205NFK58_RS23210NFK58_RS23215NFK58_RS23220NFK58_RS23225
Location: 4813207..4813965 (759 bp)
Type: Others
Protein ID: WP_123269099.1
Location: 4814087..4814773 (687 bp)
Type: Others
Protein ID: WP_137382890.1
Location: 4814770..4815906 (1137 bp)
Type: Others
Protein ID: WP_126957331.1
Location: 4815909..4816463 (555 bp)
Type: Others
Protein ID: WP_079938996.1
Location: 4816450..4816884 (435 bp)
Type: Others
Protein ID: WP_123269102.1
Location: 4816893..4817651 (759 bp)
Type: Others
Protein ID: WP_191227901.1
Location: 4817730..4817981 (252 bp)
Type: Antitoxin
Protein ID: WP_006688247.1
Location: 4817978..4818265 (288 bp)
Type: Toxin
Protein ID: WP_085049650.1
Location: 4818262..4818591 (330 bp)
Type: Others
Protein ID: WP_137361135.1
Location: 4818660..4819292 (633 bp)
Type: Others
Protein ID: WP_123269105.1
Location: 4819468..4821741 (2274 bp)
Type: Others
Protein ID: WP_123269106.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NFK58_RS23175 (NFK58_23195)4813207..4813965+759WP_123269099.1phosphonate C-P lyase system protein PhnK-
NFK58_RS23180 (NFK58_23200)4814087..4814773+687WP_137382890.1phosphonate C-P lyase system protein PhnL-
NFK58_RS23185 (NFK58_23205)4814770..4815906+1137WP_126957331.1alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase-
NFK58_RS23190 (NFK58_23210)4815909..4816463+555WP_079938996.1ribose 1,5-bisphosphokinase-
NFK58_RS23195 (NFK58_23215)4816450..4816884+435WP_123269102.1aminoalkylphosphonate N-acetyltransferase-
NFK58_RS23200 (NFK58_23220)4816893..4817651+759WP_191227901.1phosphonate metabolism protein PhnP-
NFK58_RS23205 (NFK58_23225)4817730..4817981+252WP_006688247.1plasmid stabilization proteinAntitoxin
NFK58_RS23210 (NFK58_23230)4817978..4818265+288WP_085049650.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NFK58_RS23215 (NFK58_23235)4818262..4818591-330WP_137361135.1DDRRRQL repeat protein YjdP-
NFK58_RS23220 (NFK58_23240)4818660..4819292-633WP_123269105.1GNAT family N-acetyltransferase-
NFK58_RS23225 (NFK58_23245)4819468..4821741-2274WP_123269106.1hybrid sensor histidine kinase/response regulator-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11089.04 Da        Isoelectric Point: 10.3527

>T248688 WP_085049650.1 NZ_CP099373:4817978-4818265 [Citrobacter portucalensis]
MSYTVKFREDALKEWQKLDKAIQQQFAKKLKKCCENPHVPSAKLRGIKDCYKIKLRTSGFRLVYQVIDDTLVIAVVAVGK
RERSEVYNLASERLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9215.53 Da        Isoelectric Point: 4.2965

>AT248688 WP_006688247.1 NZ_CP099373:4817730-4817981 [Citrobacter portucalensis]
MPHIILSDTTASVSELKKNPMATVSAGDGFPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVHERSQQPLVDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A7X1BT32

References