248685

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 4551456..4552264 Replicon chromosome
Accession NZ_CP099373
Organism Citrobacter portucalensis strain RHB38-SO-C05

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag NFK58_RS21815 Protein ID WP_279267840.1
Coordinates 4551456..4551833 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFK58_RS21820 Protein ID WP_279267841.1
Coordinates 4551905..4552264 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK58_RS21785 (NFK58_21805) 4547824..4548225 - 402 WP_148043815.1 Exc2 family lipoprotein -
NFK58_RS21790 (NFK58_21810) 4548454..4548745 + 292 Protein_4275 septation initiation protein -
NFK58_RS21795 (NFK58_21815) 4548872..4549669 - 798 WP_279267837.1 helix-turn-helix transcriptional regulator -
NFK58_RS21800 (NFK58_21820) 4549804..4550652 - 849 WP_279267838.1 DUF4942 domain-containing protein -
NFK58_RS21805 (NFK58_21825) 4550750..4550938 - 189 Protein_4278 hypothetical protein -
NFK58_RS21810 (NFK58_21830) 4550968..4551459 - 492 WP_279267839.1 DUF5983 family protein -
NFK58_RS21815 (NFK58_21835) 4551456..4551833 - 378 WP_279267840.1 TA system toxin CbtA family protein Toxin
NFK58_RS21820 (NFK58_21840) 4551905..4552264 - 360 WP_279267841.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFK58_RS21825 (NFK58_21845) 4552286..4552507 - 222 WP_279267842.1 DUF987 family protein -
NFK58_RS21830 (NFK58_21850) 4552504..4552983 - 480 WP_279267843.1 DNA repair protein RadC -
NFK58_RS21835 (NFK58_21855) 4552995..4553468 - 474 WP_279267844.1 antirestriction protein -
NFK58_RS21840 (NFK58_21860) 4553547..4554368 - 822 WP_279267845.1 DUF932 domain-containing protein -
NFK58_RS21845 (NFK58_21865) 4554537..4555052 - 516 WP_279267846.1 hypothetical protein -
NFK58_RS21850 (NFK58_21870) 4555058..4555609 - 552 WP_279267847.1 hypothetical protein -
NFK58_RS21855 (NFK58_21875) 4555915..4556805 - 891 WP_279267848.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4547474..4576271 28797


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13926.88 Da        Isoelectric Point: 7.9046

>T248685 WP_279267840.1 NZ_CP099373:c4551833-4551456 [Citrobacter portucalensis]
MQTQPESHRRATRPCPSPVNIWKMLLTYLLEQHYGLTLNDTPFSDEQVIAQHIDAGISLADALNFLVEKYDLVRTDRPGF
SIPHQSPFISAIDILRARKVTGLMQRTGYKAVTCAISGQSSGGQQ

Download         Length: 378 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13357.30 Da        Isoelectric Point: 7.7967

>AT248685 WP_279267841.1 NZ_CP099373:c4552264-4551905 [Citrobacter portucalensis]
MSNTIPATNYDMAEPWWGLKRNITPCFGARLVQEGNRLHYLADRASINGKFSDADLRHLDQAFPLLMKQLELMLTSGELT
PRHQHRVTLYAKGLTCDADSLASCGYVYIAIYPTPARTA

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References