Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 997705..998359 Replicon chromosome
Accession NZ_CP099373
Organism Citrobacter portucalensis strain RHB38-SO-C05

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFK58_RS04925 Protein ID WP_123267957.1
Coordinates 997952..998359 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A7W3EV23
Locus tag NFK58_RS04920 Protein ID WP_016150945.1
Coordinates 997705..997971 (+) Length 89 a.a.

Genomic Context

NFK58_RS04905NFK58_RS04910NFK58_RS04920NFK58_RS04925NFK58_RS04935NFK58_RS04940NFK58_RS04945NFK58_RS04895NFK58_RS04900NFK58_RS04915NFK58_RS04930
Location: 995195..995506 (312 bp)
Type: Others
Protein ID: WP_191228207.1
Location: 995670..996323 (654 bp)
Type: Others
Protein ID: WP_003825509.1
Location: 997705..997971 (267 bp)
Type: Antitoxin
Protein ID: WP_016150945.1
Location: 997952..998359 (408 bp)
Type: Toxin
Protein ID: WP_123267957.1
Location: 999096..999992 (897 bp)
Type: Others
Protein ID: WP_003825519.1
Location: 1000016..1000729 (714 bp)
Type: Others
Protein ID: WP_003825520.1
Location: 1000735..1002468 (1734 bp)
Type: Others
Protein ID: WP_079938629.1
Location: 992860..994293 (1434 bp)
Type: Others
Protein ID: WP_191228206.1
Location: 994414..995142 (729 bp)
Type: Others
Protein ID: WP_123268157.1
Location: 996464..997447 (984 bp)
Type: Others
Protein ID: WP_123267955.1
Location: 998461..998982 (522 bp)
Type: Others
Protein ID: WP_003026933.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NFK58_RS04895 (NFK58_04925)992860..994293-1434WP_191228206.16-phospho-beta-glucosidase BglA-
NFK58_RS04900 (NFK58_04930)994414..995142-729WP_123268157.1MurR/RpiR family transcriptional regulator-
NFK58_RS04905 (NFK58_04935)995195..995506+312WP_191228207.1N(4)-acetylcytidine aminohydrolase-
NFK58_RS04910 (NFK58_04940)995670..996323+654WP_003825509.1hemolysin III family protein-
NFK58_RS04915 (NFK58_04945)996464..997447-984WP_123267955.1tRNA-modifying protein YgfZ-
NFK58_RS04920 (NFK58_04950)997705..997971+267WP_016150945.1FAD assembly factor SdhEAntitoxin
NFK58_RS04925 (NFK58_04955)997952..998359+408WP_123267957.1protein YgfXToxin
NFK58_RS04930 (NFK58_04960)998461..998982-522WP_003026933.1flavodoxin FldB-
NFK58_RS04935 (NFK58_04965)999096..999992+897WP_003825519.1site-specific tyrosine recombinase XerD-
NFK58_RS04940 (NFK58_04970)1000016..1000729+714WP_003825520.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
NFK58_RS04945 (NFK58_04975)1000735..1002468+1734WP_079938629.1single-stranded-DNA-specific exonuclease RecJ-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15863.72 Da        Isoelectric Point: 11.0795

>T248676 WP_123267957.1 NZ_CP099373:997952-998359 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLHLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10586.14 Da        Isoelectric Point: 5.1700

>AT248676 WP_016150945.1 NZ_CP099373:997705-997971 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADVELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7W3EV23

References