Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 997705..998359 Replicon chromosome
Accession NZ_CP099373
Organism Citrobacter portucalensis strain RHB38-SO-C05

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFK58_RS04925 Protein ID WP_123267957.1
Coordinates 997952..998359 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A7W3EV23
Locus tag NFK58_RS04920 Protein ID WP_016150945.1
Coordinates 997705..997971 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK58_RS04895 (NFK58_04925) 992860..994293 - 1434 WP_191228206.1 6-phospho-beta-glucosidase BglA -
NFK58_RS04900 (NFK58_04930) 994414..995142 - 729 WP_123268157.1 MurR/RpiR family transcriptional regulator -
NFK58_RS04905 (NFK58_04935) 995195..995506 + 312 WP_191228207.1 N(4)-acetylcytidine aminohydrolase -
NFK58_RS04910 (NFK58_04940) 995670..996323 + 654 WP_003825509.1 hemolysin III family protein -
NFK58_RS04915 (NFK58_04945) 996464..997447 - 984 WP_123267955.1 tRNA-modifying protein YgfZ -
NFK58_RS04920 (NFK58_04950) 997705..997971 + 267 WP_016150945.1 FAD assembly factor SdhE Antitoxin
NFK58_RS04925 (NFK58_04955) 997952..998359 + 408 WP_123267957.1 protein YgfX Toxin
NFK58_RS04930 (NFK58_04960) 998461..998982 - 522 WP_003026933.1 flavodoxin FldB -
NFK58_RS04935 (NFK58_04965) 999096..999992 + 897 WP_003825519.1 site-specific tyrosine recombinase XerD -
NFK58_RS04940 (NFK58_04970) 1000016..1000729 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFK58_RS04945 (NFK58_04975) 1000735..1002468 + 1734 WP_079938629.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15863.72 Da        Isoelectric Point: 11.0795

>T248676 WP_123267957.1 NZ_CP099373:997952-998359 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLHLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10586.14 Da        Isoelectric Point: 5.1700

>AT248676 WP_016150945.1 NZ_CP099373:997705-997971 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADVELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7W3EV23

References