Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2653755..2654491 Replicon chromosome
Accession NZ_CP099370
Organism Citrobacter portucalensis strain RHB40-E3-C01

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag NFK62_RS13080 Protein ID WP_126318108.1
Coordinates 2654009..2654491 (+) Length 161 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag NFK62_RS13075 Protein ID WP_008784769.1
Coordinates 2653755..2654021 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK62_RS13055 (2648819) 2648819..2650006 + 1188 WP_279274735.1 outer membrane protein transport protein -
NFK62_RS13060 (2650244) 2650244..2650873 + 630 WP_003832974.1 winged helix-turn-helix transcriptional regulator -
NFK62_RS13065 (2650990) 2650990..2651376 - 387 WP_063941972.1 hypothetical protein -
NFK62_RS13070 (2651619) 2651619..2653601 + 1983 WP_149335332.1 alkyl sulfatase dimerization domain-containing protein -
NFK62_RS13075 (2653755) 2653755..2654021 + 267 WP_008784769.1 DUF1778 domain-containing protein Antitoxin
NFK62_RS13080 (2654009) 2654009..2654491 + 483 WP_126318108.1 GNAT family N-acetyltransferase Toxin
NFK62_RS13085 (2654788) 2654788..2654919 - 132 Protein_2564 fatty acid transporter -
NFK62_RS13090 (2654887) 2654887..2655672 + 786 WP_279274736.1 DMT family transporter -
NFK62_RS13095 (2655682) 2655682..2656203 - 522 WP_279275967.1 GNAT family N-acetyltransferase -
NFK62_RS13100 (2656314) 2656314..2657072 + 759 WP_126318110.1 trans-aconitate 2-methyltransferase -
NFK62_RS13105 (2657204) 2657204..2657581 + 378 WP_003832953.1 GFA family protein -
NFK62_RS13110 (2657578) 2657578..2658492 - 915 WP_063941590.1 bestrophin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(74-149)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17655.49 Da        Isoelectric Point: 9.8994

>T248671 WP_126318108.1 NZ_CP099370:2654009-2654491 [Citrobacter portucalensis]
VGFVTAPEPLTHIHRLAEFVSGEIILDDWLKQKGLKNQALGAARTFVVCKTDTRQVAGFYSLATGSVNHTEATGNLRRNM
PDPIPVIILARLAVDLSVRGKGLGADLLHDAVLRCYKVAENIGVRAVMVHALTDEAKRFYLHHGFKASQLQERTLFLRLS

Download         Length: 483 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10159.65 Da        Isoelectric Point: 4.6558

>AT248671 WP_008784769.1 NZ_CP099370:2653755-2654021 [Citrobacter portucalensis]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIEMLDAPVAEDPAIRKLL
ARKPQWDL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References