Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 837545..838199 Replicon chromosome
Accession NZ_CP099367
Organism Citrobacter portucalensis strain RHB40-E3-C05

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFK63_RS04145 Protein ID WP_003825515.1
Coordinates 837792..838199 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NFK63_RS04140 Protein ID WP_003825514.1
Coordinates 837545..837811 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK63_RS04115 (832700) 832700..834133 - 1434 WP_126956613.1 6-phospho-beta-glucosidase BglA -
NFK63_RS04120 (834254) 834254..834982 - 729 WP_279275949.1 MurR/RpiR family transcriptional regulator -
NFK63_RS04125 (835035) 835035..835346 + 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
NFK63_RS04130 (835510) 835510..836172 + 663 WP_279275505.1 hemolysin III family protein -
NFK63_RS04135 (836304) 836304..837287 - 984 WP_126317440.1 tRNA-modifying protein YgfZ -
NFK63_RS04140 (837545) 837545..837811 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
NFK63_RS04145 (837792) 837792..838199 + 408 WP_003825515.1 protein YgfX Toxin
NFK63_RS04150 (838301) 838301..838822 - 522 WP_279275506.1 flavodoxin FldB -
NFK63_RS04155 (838936) 838936..839832 + 897 WP_126317441.1 site-specific tyrosine recombinase XerD -
NFK63_RS04160 (839856) 839856..840569 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFK63_RS04165 (840575) 840575..842308 + 1734 WP_126317443.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T248656 WP_003825515.1 NZ_CP099367:837792-838199 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT248656 WP_003825514.1 NZ_CP099367:837545-837811 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References