Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4280861..4281380 Replicon chromosome
Accession NZ_CP099364
Organism Citrobacter braakii strain RHB44-SE-C08

Toxin (Protein)


Gene name relE Uniprot ID A0A8I0G602
Locus tag NFL11_RS20930 Protein ID WP_047414720.1
Coordinates 4280861..4281142 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFL11_RS20935 Protein ID WP_049270661.1
Coordinates 4281132..4281380 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFL11_RS20915 (4277863) 4277863..4278327 + 465 WP_016155562.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFL11_RS20920 (4278349) 4278349..4278870 - 522 WP_019078246.1 hypothetical protein -
NFL11_RS20925 (4278870) 4278870..4280834 - 1965 WP_109017766.1 type VI secretion system tip protein TssI/VgrG -
NFL11_RS20930 (4280861) 4280861..4281142 - 282 WP_047414720.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFL11_RS20935 (4281132) 4281132..4281380 - 249 WP_049270661.1 plasmid stabilization protein Antitoxin
NFL11_RS20940 (4281478) 4281478..4281606 - 129 WP_256372910.1 hypothetical protein -
NFL11_RS20945 (4281675) 4281675..4282148 - 474 WP_016155556.1 hypothetical protein -
NFL11_RS20950 (4282191) 4282191..4284692 - 2502 WP_279268279.1 type VI secretion system ATPase TssH -
NFL11_RS20955 (4284683) 4284683..4285630 - 948 WP_279268280.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10974.73 Da        Isoelectric Point: 10.4466

>T248639 WP_047414720.1 NZ_CP099364:c4281142-4280861 [Citrobacter braakii]
MTYNLEFLDVALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9003.28 Da        Isoelectric Point: 4.7513

>AT248639 WP_049270661.1 NZ_CP099364:c4281380-4281132 [Citrobacter braakii]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELAEDAELNRISDEREGGKRIKVSLN
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References