Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 57041..57720 Replicon chromosome
Accession NZ_CP099364
Organism Citrobacter braakii strain RHB44-SE-C08

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag NFL11_RS00290 Protein ID WP_279268341.1
Coordinates 57041..57382 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NFL11_RS00295 Protein ID WP_279268342.1
Coordinates 57403..57720 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFL11_RS00265 (52263) 52263..53243 + 981 WP_000019403.1 IS5-like element IS5 family transposase -
NFL11_RS00270 (53281) 53281..53967 - 687 WP_279268338.1 AIPR family protein -
NFL11_RS00280 (54808) 54808..55335 - 528 WP_279268339.1 hypothetical protein -
NFL11_RS00285 (56047) 56047..56748 + 702 WP_279268340.1 toll/interleukin-1 receptor domain-containing protein -
NFL11_RS00290 (57041) 57041..57382 - 342 WP_279268341.1 TA system toxin CbtA family protein Toxin
NFL11_RS00295 (57403) 57403..57720 - 318 WP_279268342.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFL11_RS00300 (57739) 57739..57960 - 222 WP_279268343.1 DUF987 domain-containing protein -
NFL11_RS00305 (57969) 57969..58445 - 477 WP_279268344.1 RadC family protein -
NFL11_RS00310 (58461) 58461..58793 - 333 Protein_61 antirestriction protein -
NFL11_RS00315 (58744) 58744..60555 - 1812 WP_279268733.1 AIDA repeat-containing protein -
NFL11_RS00320 (60618) 60618..61301 - 684 WP_279268345.1 WYL domain-containing protein -
NFL11_RS00325 (61529) 61529..62356 - 828 WP_279268346.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12759.65 Da        Isoelectric Point: 8.9789

>T248629 WP_279268341.1 NZ_CP099364:c57382-57041 [Citrobacter braakii]
MKSLPATTSRTAKSCLSPVAVWQMLLTRLLEKHYGLTLNDTPFSDETVIQEHIDAGITLADAINFLVEKYELVRIDRKGF
SWQEQSPYLRAVDILRARQATGLLRQSRNNAVG

Download         Length: 342 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11956.57 Da        Isoelectric Point: 6.6286

>AT248629 WP_279268342.1 NZ_CP099364:c57720-57403 [Citrobacter braakii]
MSNITWGLQRDITPRLGARLVQEGNQLHYLADRASITGKFSDAECRKLDETFPHFISRMESMLTTGEMNPRHAHCVILYH
NGFTCEADTLGSYGYVYIAIYPTQL

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References