Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1400278..1400770 Replicon chromosome
Accession NC_014363
Organism Olsenella uli DSM 7084

Toxin (Protein)


Gene name pasB Uniprot ID E1QW35
Locus tag OLSU_RS06160 Protein ID WP_013252090.1
Coordinates 1400278..1400550 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID X8HUM6
Locus tag OLSU_RS06165 Protein ID WP_013252091.1
Coordinates 1400534..1400770 (-) Length 79 a.a.

Genomic Context

OLSU_RS09640OLSU_RS06175OLSU_RS06180OLSU_RS06135OLSU_RS09635OLSU_RS06140OLSU_RS06145OLSU_RS09120OLSU_RS06160OLSU_RS06165OLSU_RS09125OLSU_RS09645
Location: 1401643..1401789 (147 bp)
Type: Others
Protein ID: WP_156407852.1
Location: 1401799..1403361 (1563 bp)
Type: Others
Protein ID: WP_013252093.1
Location: 1403398..1403613 (216 bp)
Type: Others
Protein ID: WP_013252094.1
Location: 1395740..1396510 (771 bp)
Type: Others
Protein ID: WP_013252084.1
Location: 1396543..1396698 (156 bp)
Type: Others
Protein ID: WP_013252085.1
Location: 1396912..1397997 (1086 bp)
Type: Others
Protein ID: WP_013252086.1
Location: 1397994..1398662 (669 bp)
Type: Others
Protein ID: WP_013252087.1
Location: 1398730..1399578 (849 bp)
Type: Others
Protein ID: WP_013252088.1
Location: 1400278..1400550 (273 bp)
Type: Toxin
Protein ID: WP_013252090.1
Location: 1400534..1400770 (237 bp)
Type: Antitoxin
Protein ID: WP_013252091.1
Location: 1401106..1401399 (294 bp)
Type: Others
Protein ID: WP_162260679.1
Location: 1403610..1403786 (177 bp)
Type: Others
Protein ID: WP_013252095.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OLSU_RS061351395740..1396510-771WP_013252084.1ABC transporter ATP-binding protein-
OLSU_RS096351396543..1396698-156WP_013252085.1hypothetical protein-
OLSU_RS061401396912..1397997-1086WP_013252086.1sensor histidine kinase-
OLSU_RS061451397994..1398662-669WP_013252087.1response regulator transcription factor-
OLSU_RS091201398730..1399578-849WP_013252088.1hypothetical protein-
OLSU_RS061601400278..1400550-273WP_013252090.1type II toxin-antitoxin system RelE/ParE family toxinToxin
OLSU_RS061651400534..1400770-237WP_013252091.1hypothetical proteinAntitoxin
OLSU_RS091251401106..1401399-294WP_162260679.1helix-turn-helix transcriptional regulator-
OLSU_RS096401401643..1401789+147WP_156407852.1hypothetical protein-
OLSU_RS061751401799..1403361+1563WP_013252093.1terminase-
OLSU_RS061801403398..1403613+216WP_013252094.1hypothetical protein-
OLSU_RS096451403610..1403786-177WP_013252095.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10662.34 Da        Isoelectric Point: 10.8094

>T24854 WP_013252090.1 NC_014363:c1400550-1400278 [Olsenella uli DSM 7084]
VAWRIKFTKAADKALRRLDRSVSSRILDELESVSKLEDPRTRGRALRHNLSGLWRYRVGDHRIVCDMEDEVLLVLVVDVA
HRREVYKRHK

Download         Length: 273 bp

>T24854 NC_014363:c1400550-1400278 [Olsenella uli DSM 7084]
GTGGCCTGGAGGATTAAGTTCACAAAGGCCGCCGACAAGGCCCTGCGACGGCTCGATCGCTCGGTCTCGTCGAGGATTCT
CGACGAGCTTGAGAGTGTGTCGAAACTCGAAGACCCCCGCACAAGAGGAAGGGCCCTGAGACACAACCTGTCGGGCTTGT
GGCGCTATCGGGTCGGCGACCACCGCATCGTGTGCGACATGGAGGACGAGGTTCTCTTGGTTCTCGTGGTCGATGTGGCC
CACAGGCGCGAGGTCTACAAGCGCCACAAATGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8984.11 Da        Isoelectric Point: 4.5216

>AT24854 WP_013252091.1 NC_014363:c1400770-1400534 [Olsenella uli DSM 7084]
METATAALRMPKELVARYDQLAKSTGRTKTFYMTEALAESIDRLEYEYGILKDIEDYRAGRLETYSLDEVRAHCGLED

Download         Length: 237 bp

>AT24854 NC_014363:c1400770-1400534 [Olsenella uli DSM 7084]
ATGGAAACTGCGACTGCGGCATTGAGAATGCCTAAGGAGCTGGTCGCAAGGTACGACCAGCTGGCAAAGTCTACGGGGCG
CACGAAGACGTTCTATATGACCGAGGCCCTTGCGGAGTCCATCGACAGGCTCGAGTACGAGTACGGAATCCTCAAGGACA
TCGAAGACTATCGAGCGGGGCGGCTAGAGACCTACAGCCTCGATGAGGTGAGGGCGCACTGTGGCCTGGAGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBE1QW35

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBX8HUM6

References