Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1919161..1919429 Replicon chromosome
Accession NZ_CP099338
Organism Escherichia fergusonii strain RHB44-C01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1919288..1919391 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1919161..1919429 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK94_RS09090 1915711..1916373 - 663 WP_000946659.1 exodeoxyribonuclease X -
NFK94_RS09095 1916397..1917053 - 657 WP_104919666.1 carbon-nitrogen hydrolase family protein -
NFK94_RS09100 1917160..1917390 - 231 WP_000700614.1 DNA polymerase III subunit theta -
NFK94_RS09105 1917529..1917903 + 375 WP_000168725.1 CopC domain-containing protein YobA -
NFK94_RS09110 1917906..1918778 + 873 WP_000928496.1 copper homeostasis membrane protein CopD -
NFK94_RS09115 1918790..1919131 + 342 WP_000976177.1 YebY family protein -
- 1919161..1919429 - 269 - - Antitoxin
- 1919288..1919391 + 104 - - Toxin
NFK94_RS09120 1919525..1920181 + 657 Protein_1770 protein-serine/threonine phosphatase -
NFK94_RS09125 1920182..1920373 - 192 WP_001296140.1 YebW family protein -
NFK94_RS09130 1920478..1920714 - 237 WP_001295499.1 YebV family protein -
NFK94_RS09135 1920832..1922271 - 1440 WP_002432103.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1913654..1935458 21804


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T248527 NZ_CP099338:1919288-1919391 [Escherichia fergusonii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT248527 NZ_CP099338:c1919429-1919161 [Escherichia fergusonii]
AAAGTCAGCGAATGGAATATTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References