Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3886903..3887560 Replicon chromosome
Accession NZ_CP099325
Organism Enterobacter ludwigii strain RHB47-SO-C01

Toxin (Protein)


Gene name cptA Uniprot ID G8LDB6
Locus tag NFL61_RS18390 Protein ID WP_014171514.1
Coordinates 3886903..3887313 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag NFL61_RS18395 Protein ID WP_003863437.1
Coordinates 3887294..3887560 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFL61_RS18370 (NFL61_18365) 3882901..3884634 - 1734 WP_279258609.1 single-stranded-DNA-specific exonuclease RecJ -
NFL61_RS18375 (NFL61_18370) 3884640..3885353 - 714 WP_020883731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFL61_RS18380 (NFL61_18375) 3885377..3886273 - 897 WP_014171511.1 site-specific tyrosine recombinase XerD -
NFL61_RS18385 (NFL61_18380) 3886375..3886896 + 522 WP_183516698.1 flavodoxin FldB -
NFL61_RS18390 (NFL61_18385) 3886903..3887313 - 411 WP_014171514.1 protein YgfX Toxin
NFL61_RS18395 (NFL61_18390) 3887294..3887560 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
NFL61_RS18400 (NFL61_18395) 3887855..3888835 + 981 WP_020883730.1 tRNA-modifying protein YgfZ -
NFL61_RS18405 (NFL61_18400) 3888946..3889605 - 660 WP_014171517.1 hemolysin III family protein -
NFL61_RS18410 (NFL61_18405) 3889872..3890603 + 732 WP_086532136.1 MurR/RpiR family transcriptional regulator -
NFL61_RS18415 (NFL61_18410) 3890720..3892153 + 1434 WP_032678925.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16217.15 Da        Isoelectric Point: 11.5020

>T248456 WP_014171514.1 NZ_CP099325:c3887313-3886903 [Enterobacter ludwigii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRIHARQGEIKLLMDSRLRWQGK
EWEILGMPWMIASGMMLRLRSVDSGRRQHLWLAADSMDSAEWRDLRRMLLQQLTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT248456 WP_003863437.1 NZ_CP099325:c3887560-3887294 [Enterobacter ludwigii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A839BUV6

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References