Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | KacT-ataR/DUF1778(antitoxin) |
Location | 1695927..1696724 | Replicon | chromosome |
Accession | NZ_CP099314 | ||
Organism | Enterobacter hormaechei strain RHB44-SE-C01 |
Toxin (Protein)
Gene name | KacT | Uniprot ID | A0A4Q2R3N2 |
Locus tag | NFL05_RS07965 | Protein ID | WP_032670168.1 |
Coordinates | 1696203..1696724 (+) | Length | 174 a.a. |
Antitoxin (Protein)
Gene name | ataR | Uniprot ID | A0A331QJY7 |
Locus tag | NFL05_RS07960 | Protein ID | WP_015570876.1 |
Coordinates | 1695927..1696196 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NFL05_RS07925 (NFL05_07920) | 1691467..1691826 | + | 360 | WP_017384779.1 | helix-turn-helix domain-containing protein | - |
NFL05_RS07930 (NFL05_07925) | 1691905..1692000 | - | 96 | Protein_1536 | transcriptional regulator | - |
NFL05_RS07935 (NFL05_07930) | 1692153..1693394 | + | 1242 | WP_039271154.1 | bifunctional glucose-1-phosphatase/inositol phosphatase | - |
NFL05_RS07940 (NFL05_07935) | 1693427..1693654 | - | 228 | WP_006809324.1 | YccJ family protein | - |
NFL05_RS07945 (NFL05_07940) | 1693673..1694269 | - | 597 | WP_006809323.1 | NAD(P)H:quinone oxidoreductase | - |
NFL05_RS07950 (NFL05_07945) | 1694661..1694831 | + | 171 | WP_001273664.1 | general stress protein | - |
NFL05_RS07955 (NFL05_07950) | 1694948..1695853 | + | 906 | WP_017693666.1 | DMT family transporter | - |
NFL05_RS07960 (NFL05_07955) | 1695927..1696196 | + | 270 | WP_015570876.1 | DUF1778 domain-containing protein | Antitoxin |
NFL05_RS07965 (NFL05_07960) | 1696203..1696724 | + | 522 | WP_032670168.1 | GNAT family N-acetyltransferase | Toxin |
NFL05_RS07970 (NFL05_07965) | 1696783..1698105 | - | 1323 | WP_045344078.1 | pyrimidine utilization transport protein G | - |
NFL05_RS07975 (NFL05_07970) | 1698127..1698618 | - | 492 | WP_015570873.1 | pyrimidine utilization flavin reductase protein F | - |
NFL05_RS07980 (NFL05_07975) | 1698631..1699221 | - | 591 | WP_045344080.1 | malonic semialdehyde reductase | - |
NFL05_RS07985 (NFL05_07980) | 1699231..1700031 | - | 801 | WP_048229399.1 | pyrimidine utilization protein D | - |
NFL05_RS07990 (NFL05_07985) | 1700039..1700425 | - | 387 | WP_015570870.1 | pyrimidine utilization protein C | - |
NFL05_RS07995 (NFL05_07990) | 1700437..1701126 | - | 690 | WP_045344084.1 | pyrimidine utilization protein B | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 174 a.a. Molecular weight: 19437.18 Da Isoelectric Point: 7.4318
>T248405 WP_032670168.1 NZ_CP099314:1696203-1696724 [Enterobacter hormaechei]
VANLTIEMLSEGTDYDFGDFDCGEPSLNAFLTEHLVRQHGGRILRGYLLKERDHPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAVHKELQGNEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKLGFIPLAGENSSSLF
FPTQSIERLFEQA
VANLTIEMLSEGTDYDFGDFDCGEPSLNAFLTEHLVRQHGGRILRGYLLKERDHPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAVHKELQGNEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKLGFIPLAGENSSSLF
FPTQSIERLFEQA
Download Length: 522 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4Q2R3N2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A331QJY7 |