Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4258589..4259350 Replicon chromosome
Accession NZ_CP099311
Organism Enterobacter ludwigii strain RHB43-SE-C05

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NFK84_RS20615 Protein ID WP_279261683.1
Coordinates 4258973..4259350 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFK84_RS20610 Protein ID WP_279261682.1
Coordinates 4258589..4258948 (+) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK84_RS20565 (NFK84_20550) 4253594..4254301 + 708 WP_279261673.1 transcriptional regulator -
NFK84_RS20570 (NFK84_20555) 4254298..4254864 + 567 WP_279261674.1 hypothetical protein -
NFK84_RS20575 (NFK84_20560) 4254904..4255356 + 453 WP_279261675.1 hypothetical protein -
NFK84_RS20580 (NFK84_20565) 4255353..4255793 + 441 WP_279261676.1 IrmA family protein -
NFK84_RS20585 (NFK84_20570) 4255923..4256741 + 819 WP_279261677.1 DUF932 domain-containing protein -
NFK84_RS20590 (NFK84_20575) 4256820..4257299 + 480 WP_279261678.1 antirestriction protein -
NFK84_RS20595 (NFK84_20580) 4257412..4257855 + 444 WP_279261679.1 antirestriction protein -
NFK84_RS20600 (NFK84_20585) 4257852..4258331 + 480 WP_279261680.1 DNA repair protein RadC -
NFK84_RS20605 (NFK84_20590) 4258345..4258566 + 222 WP_279261681.1 DUF987 domain-containing protein -
NFK84_RS20610 (NFK84_20595) 4258589..4258948 + 360 WP_279261682.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFK84_RS20615 (NFK84_20600) 4258973..4259350 + 378 WP_279261683.1 TA system toxin CbtA family protein Toxin
NFK84_RS20620 (NFK84_20605) 4259347..4259838 + 492 WP_279261684.1 DUF5983 family protein -
NFK84_RS20625 (NFK84_20610) 4259862..4260065 + 204 WP_279261685.1 hypothetical protein -
NFK84_RS20630 (NFK84_20615) 4260146..4260991 + 846 WP_279261686.1 DUF4942 domain-containing protein -
NFK84_RS20635 (NFK84_20620) 4261003..4261278 + 276 WP_279261687.1 hypothetical protein -
NFK84_RS20640 (NFK84_20625) 4261286..4261813 - 528 WP_044857798.1 LuxR C-terminal-related transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13886.66 Da        Isoelectric Point: 8.0719

>T248401 WP_279261683.1 NZ_CP099311:4258973-4259350 [Enterobacter ludwigii]
MKTQSASATRAAPSRPSPVEIWQQLLSHLLDQHYGLTLNDTPFGNDSVIQEHIDAGISLCDAVNFIVEKYDLVRTDRRGF
SAETQSPLIGSIDILRARKATGLMTRHSYRAVTDITTGKYRGVQQ

Download         Length: 378 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13260.08 Da        Isoelectric Point: 6.6244

>AT248401 WP_279261682.1 NZ_CP099311:4258589-4258948 [Enterobacter ludwigii]
MSNKTRPDSHDIADPWWGLKRNITPCFGARLVQEGNRLHYLNDRASITGTFTDADLCHLDQAFPLLLKQLELMLTSGELN
PRHQHCVTLYAKGLTCEADSLGSNGYIYLVIYPTPATAA

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References