Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4035591..4036248 Replicon chromosome
Accession NZ_CP099311
Organism Enterobacter ludwigii strain RHB43-SE-C05

Toxin (Protein)


Gene name cptA Uniprot ID G8LDB6
Locus tag NFK84_RS19395 Protein ID WP_014171514.1
Coordinates 4035591..4036001 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NFK84_RS19400 Protein ID WP_279261572.1
Coordinates 4035982..4036248 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK84_RS19375 (NFK84_19355) 4031589..4033322 - 1734 WP_279261571.1 single-stranded-DNA-specific exonuclease RecJ -
NFK84_RS19380 (NFK84_19360) 4033328..4034041 - 714 WP_020883731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFK84_RS19385 (NFK84_19365) 4034065..4034961 - 897 WP_014171511.1 site-specific tyrosine recombinase XerD -
NFK84_RS19390 (NFK84_19370) 4035063..4035584 + 522 WP_014171513.1 flavodoxin FldB -
NFK84_RS19395 (NFK84_19375) 4035591..4036001 - 411 WP_014171514.1 protein YgfX Toxin
NFK84_RS19400 (NFK84_19380) 4035982..4036248 - 267 WP_279261572.1 FAD assembly factor SdhE Antitoxin
NFK84_RS19405 (NFK84_19385) 4036543..4037523 + 981 WP_020883730.1 tRNA-modifying protein YgfZ -
NFK84_RS19410 (NFK84_19390) 4037633..4038292 - 660 WP_014171517.1 hemolysin III family protein -
NFK84_RS19415 (NFK84_19395) 4038559..4039290 + 732 WP_040018863.1 MurR/RpiR family transcriptional regulator -
NFK84_RS19420 (NFK84_19400) 4039407..4040840 + 1434 WP_047743596.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16217.15 Da        Isoelectric Point: 11.5020

>T248399 WP_014171514.1 NZ_CP099311:c4036001-4035591 [Enterobacter ludwigii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRIHARQGEIKLLMDSRLRWQGK
EWEILGMPWMIASGMMLRLRSVDSGRRQHLWLAADSMDSAEWRDLRRMLLQQLTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10559.02 Da        Isoelectric Point: 4.8310

>AT248399 WP_279261572.1 NZ_CP099311:c4036248-4035982 [Enterobacter ludwigii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPMAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A839BUV6

Antitoxin

Source ID Structure

References