Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 533269..533948 Replicon chromosome
Accession NZ_CP099311
Organism Enterobacter ludwigii strain RHB43-SE-C05

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NFK84_RS02520 Protein ID WP_063444358.1
Coordinates 533628..533948 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFK84_RS02515 Protein ID WP_063444359.1
Coordinates 533269..533592 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK84_RS02485 (NFK84_02485) 528749..529624 + 876 WP_130992583.1 GTPase family protein -
NFK84_RS02490 (NFK84_02490) 529837..530538 + 702 WP_045341624.1 WYL domain-containing protein -
NFK84_RS02495 (NFK84_02495) 530544..531191 + 648 WP_063444361.1 hypothetical protein -
NFK84_RS02500 (NFK84_02500) 531374..531784 + 411 WP_279262245.1 IrmA family protein -
NFK84_RS02505 (NFK84_02505) 531894..532715 + 822 WP_045341626.1 DUF932 domain-containing protein -
NFK84_RS02510 (NFK84_02510) 532786..533256 + 471 WP_063444360.1 DNA repair protein RadC -
NFK84_RS02515 (NFK84_02515) 533269..533592 + 324 WP_063444359.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFK84_RS02520 (NFK84_02520) 533628..533948 + 321 WP_063444358.1 TA system toxin CbtA family protein Toxin
NFK84_RS02525 (NFK84_02525) 534062..534907 + 846 WP_279261867.1 DUF4942 domain-containing protein -
NFK84_RS02530 (NFK84_02530) 535119..535994 - 876 WP_121339956.1 HNH endonuclease -
NFK84_RS02535 (NFK84_02535) 536295..536747 + 453 WP_074147066.1 SymE family type I addiction module toxin -
NFK84_RS02540 (NFK84_02540) 536843..537589 - 747 WP_279261868.1 class I SAM-dependent methyltransferase -
NFK84_RS02545 (NFK84_02545) 537600..537857 - 258 WP_014168433.1 YjhX family toxin -
NFK84_RS02550 (NFK84_02550) 538147..538719 - 573 WP_279261869.1 DUF1349 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11982.64 Da        Isoelectric Point: 6.3214

>T248393 WP_063444358.1 NZ_CP099311:533628-533948 [Enterobacter ludwigii]
MHISAVPATVPVSSRLSPVQVWQQLLTYLLDHHYGLTLNDTPFHDDAAIKEHIDAGITLADAVNFLVERYELVRIDRKGF
SWQEQTPFLTATDILRARRATGLINT

Download         Length: 321 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12082.77 Da        Isoelectric Point: 6.6314

>AT248393 WP_063444359.1 NZ_CP099311:533269-533592 [Enterobacter ludwigii]
MSITPPHEWGLQSDITPRFGARLVQEGNRLHYLADRAGLTGSFSPIHLQKLDQAFPLFIEQLENMLRVGELNPHQQYHVT
IQLASLTCIADTRGSCGYVYISIYPTQ

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References