Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 484213..484729 Replicon chromosome
Accession NZ_CP099310
Organism Enterobacter ludwigii strain RHB28-E3-C01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFK33_RS02295 Protein ID WP_032681845.1
Coordinates 484445..484729 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFK33_RS02290 Protein ID WP_032679513.1
Coordinates 484213..484455 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK33_RS02275 (NFK33_02275) 480210..480950 + 741 WP_020882900.1 KDGP aldolase family protein -
NFK33_RS02280 (NFK33_02280) 481069..482205 + 1137 WP_032681848.1 lactonase family protein -
NFK33_RS02285 (NFK33_02285) 482225..484135 + 1911 WP_032681846.1 PRD domain-containing protein -
NFK33_RS02290 (NFK33_02290) 484213..484455 + 243 WP_032679513.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NFK33_RS02295 (NFK33_02295) 484445..484729 + 285 WP_032681845.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFK33_RS02300 (NFK33_02300) 484733..485197 - 465 WP_059306428.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFK33_RS02305 (NFK33_02305) 485336..487474 - 2139 WP_020885401.1 anaerobic ribonucleoside-triphosphate reductase -
NFK33_RS02310 (NFK33_02310) 487842..488414 - 573 WP_279256604.1 PTS sugar transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10904.66 Da        Isoelectric Point: 10.1940

>T248386 WP_032681845.1 NZ_CP099310:484445-484729 [Enterobacter ludwigii]
MTYELVFDPRAFKEWTRLGDTVKNQFKKKLANVLVNPRVESARLHGLPDCDKIKLRSQGYRLVYQVQDNVVTVCVIAIGK
RENSAVYHDVNKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9094.50 Da        Isoelectric Point: 5.8374

>AT248386 WP_032679513.1 NZ_CP099310:484213-484455 [Enterobacter ludwigii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDELIHTVRERLANPQKGIKVRLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References