Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3824791..3825448 Replicon chromosome
Accession NZ_CP099309
Organism Enterobacter ludwigii strain RHB25-E3-C07

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFK27_RS18095 Protein ID WP_086532137.1
Coordinates 3824791..3825201 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag NFK27_RS18100 Protein ID WP_003863437.1
Coordinates 3825182..3825448 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK27_RS18075 (NFK27_18070) 3820789..3822522 - 1734 WP_279259836.1 single-stranded-DNA-specific exonuclease RecJ -
NFK27_RS18080 (NFK27_18075) 3822528..3823241 - 714 WP_020883731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFK27_RS18085 (NFK27_18080) 3823265..3824161 - 897 WP_014171511.1 site-specific tyrosine recombinase XerD -
NFK27_RS18090 (NFK27_18085) 3824263..3824784 + 522 WP_049023375.1 flavodoxin FldB -
NFK27_RS18095 (NFK27_18090) 3824791..3825201 - 411 WP_086532137.1 protein YgfX Toxin
NFK27_RS18100 (NFK27_18095) 3825182..3825448 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
NFK27_RS18105 (NFK27_18100) 3825743..3826723 + 981 WP_032678924.1 tRNA-modifying protein YgfZ -
NFK27_RS18110 (NFK27_18105) 3826833..3827492 - 660 WP_014171517.1 hemolysin III family protein -
NFK27_RS18115 (NFK27_18110) 3827759..3828490 + 732 WP_020883729.1 MurR/RpiR family transcriptional regulator -
NFK27_RS18120 (NFK27_18115) 3828607..3830040 + 1434 WP_032678925.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16199.12 Da        Isoelectric Point: 11.5020

>T248385 WP_086532137.1 NZ_CP099309:c3825201-3824791 [Enterobacter ludwigii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRIHARQGEIKLLMDSRLRWQGK
EWEILGLPWMIASGMMLRLRSVDSGRRQHLWLAADSMDSAEWRDLRRMLLQQLTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT248385 WP_003863437.1 NZ_CP099309:c3825448-3825182 [Enterobacter ludwigii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References