Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 461619..462090 Replicon chromosome
Accession NZ_CP099309
Organism Enterobacter ludwigii strain RHB25-E3-C07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFK27_RS02180 Protein ID WP_279260158.1
Coordinates 461851..462090 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFK27_RS02175 Protein ID WP_079231472.1
Coordinates 461619..461861 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK27_RS02160 (NFK27_02160) 457649..458389 + 741 WP_059306432.1 KDGP aldolase family protein -
NFK27_RS02165 (NFK27_02165) 458475..459611 + 1137 WP_279260155.1 lactonase family protein -
NFK27_RS02170 (NFK27_02170) 459631..461541 + 1911 WP_279260156.1 PRD domain-containing protein -
NFK27_RS02175 (NFK27_02175) 461619..461861 + 243 WP_079231472.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NFK27_RS02180 (NFK27_02180) 461851..462090 + 240 WP_279260158.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFK27_RS02185 (NFK27_02185) 462139..462603 - 465 WP_063157014.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFK27_RS02190 (NFK27_02190) 462742..464880 - 2139 WP_279260159.1 anaerobic ribonucleoside-triphosphate reductase -
NFK27_RS02195 (NFK27_02195) 465248..465820 - 573 WP_032679517.1 PTS sugar transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-77)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9157.72 Da        Isoelectric Point: 9.8323

>T248378 WP_279260158.1 NZ_CP099309:461851-462090 [Enterobacter ludwigii]
MSYELVFDPRAFKEWTRLGDTVKNQFKKKLANVLVNPWVESARLHGLPDCYKIKLRSQGYRLVYQVQDNVVTVCVIAIG

Download         Length: 240 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9100.50 Da        Isoelectric Point: 4.8146

>AT248378 WP_079231472.1 NZ_CP099309:461619-461861 [Enterobacter ludwigii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDELIQTVRERLADPQKGIKVRLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References