248366

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4759416..4760235 Replicon chromosome
Accession NZ_CP099306
Organism Klebsiella michiganensis strain RHB20-SO-C01

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag NFK05_RS22495 Protein ID WP_004110819.1
Coordinates 4759978..4760235 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag NFK05_RS22490 Protein ID WP_181251206.1
Coordinates 4759416..4759967 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK05_RS22470 (NFK05_22450) 4754786..4756183 + 1398 WP_014228060.1 MFS transporter -
NFK05_RS22475 (NFK05_22455) 4756305..4757645 + 1341 WP_032748099.1 carbohydrate porin -
NFK05_RS22480 (NFK05_22460) 4757770..4758516 - 747 WP_227502786.1 class I SAM-dependent methyltransferase -
NFK05_RS22485 (NFK05_22465) 4758940..4759302 - 363 Protein_4427 class I SAM-dependent methyltransferase -
NFK05_RS22490 (NFK05_22470) 4759416..4759967 - 552 WP_181251206.1 N-acetyltransferase Antitoxin
NFK05_RS22495 (NFK05_22475) 4759978..4760235 - 258 WP_004110819.1 YjhX family toxin Toxin
NFK05_RS22500 (NFK05_22480) 4760911..4762095 + 1185 WP_014228054.1 mannonate dehydratase -
NFK05_RS22505 (NFK05_22485) 4762169..4763644 + 1476 WP_014228053.1 fructuronate reductase -
NFK05_RS22510 (NFK05_22490) 4763783..4764559 + 777 WP_004847986.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T248366 WP_004110819.1 NZ_CP099306:c4760235-4759978 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19962.69 Da        Isoelectric Point: 6.4913

>AT248366 WP_181251206.1 NZ_CP099306:c4759967-4759416 [Klebsiella michiganensis]
MTNHSFTFHVTSEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLTVVPEYQGAGVGGELIRHGIEQLKAMGSQAVFVLGHAAYYPRHGFEPGAGDKGYPAPYPIPAAHKACWMLQPISS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References