Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2248952..2249120 Replicon chromosome
Accession NZ_CP099306
Organism Klebsiella michiganensis strain RHB20-SO-C01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2249010..2249113 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2248952..2249120 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK05_RS10735 (NFK05_10730) 2244079..2246139 + 2061 WP_143439875.1 oligopeptidase B -
NFK05_RS10740 (NFK05_10735) 2246146..2246805 - 660 WP_014229839.1 exodeoxyribonuclease X -
NFK05_RS10745 (NFK05_10740) 2246884..2247114 - 231 WP_004103351.1 DNA polymerase III subunit theta -
NFK05_RS10750 (NFK05_10745) 2247250..2247624 + 375 WP_014229838.1 CopC domain-containing protein YobA -
NFK05_RS10755 (NFK05_10750) 2247629..2248498 + 870 WP_025106130.1 copper homeostasis membrane protein CopD -
NFK05_RS10760 (NFK05_10755) 2248515..2248853 + 339 WP_004103344.1 YebY family protein -
- 2248952..2249120 - 169 - - Antitoxin
- 2249010..2249113 + 104 - - Toxin
NFK05_RS10765 (NFK05_10760) 2249238..2250197 - 960 WP_025106131.1 spore coat protein U domain-containing protein -
NFK05_RS10770 (NFK05_10765) 2250212..2252542 - 2331 WP_143439874.1 fimbria/pilus outer membrane usher protein -
NFK05_RS10775 (NFK05_10770) 2252545..2253309 - 765 WP_134897814.1 fimbria/pilus periplasmic chaperone -
NFK05_RS10780 (NFK05_10775) 2253328..2253846 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T248361 NZ_CP099306:2249010-2249113 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT248361 NZ_CP099306:c2249120-2248952 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References