Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4217464..4217980 Replicon chromosome
Accession NZ_CP099303
Organism Citrobacter freundii strain RHB02-E1-C01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFJ16_RS20090 Protein ID WP_048216920.1
Coordinates 4217464..4217748 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0J1MV10
Locus tag NFJ16_RS20095 Protein ID WP_003839576.1
Coordinates 4217738..4217980 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ16_RS20075 (4213789) 4213789..4214373 + 585 WP_003839584.1 fructose PTS transporter subunit IIA -
NFJ16_RS20080 (4214751) 4214751..4216889 + 2139 WP_003839582.1 anaerobic ribonucleoside-triphosphate reductase -
NFJ16_RS20085 (4216996) 4216996..4217460 + 465 WP_032937736.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFJ16_RS20090 (4217464) 4217464..4217748 - 285 WP_048216920.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFJ16_RS20095 (4217738) 4217738..4217980 - 243 WP_003839576.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NFJ16_RS20100 (4218058) 4218058..4219971 - 1914 WP_048241736.1 BglG family transcription antiterminator -
NFJ16_RS20105 (4219993) 4219993..4220733 - 741 WP_129622263.1 KDGP aldolase family protein -
NFJ16_RS20110 (4220730) 4220730..4221848 - 1119 WP_048216923.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
NFJ16_RS20115 (4221832) 4221832..4222965 - 1134 WP_048216924.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10905.80 Da        Isoelectric Point: 10.1715

>T248344 WP_048216920.1 NZ_CP099303:c4217748-4217464 [Citrobacter freundii]
MTYELEFDPRALKEWHKLGDKVKAQFKKKLADVLLNPRIDSARLNGLPDCYKIKLKSSGYRLVYQVRDEVVIVFVVAVGK
REHSAVYLDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT248344 WP_003839576.1 NZ_CP099303:c4217980-4217738 [Citrobacter freundii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDTLIQTVRERLASPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0J1MV10

References