Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4154072..4154752 Replicon chromosome
Accession NZ_CP099303
Organism Citrobacter freundii strain RHB02-E1-C01

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NFJ16_RS19805 Protein ID WP_279264317.1
Coordinates 4154072..4154392 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFJ16_RS19810 Protein ID WP_186557010.1
Coordinates 4154429..4154752 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ16_RS19780 (4149806) 4149806..4150168 + 363 WP_032937671.1 endoribonuclease SymE -
NFJ16_RS19785 (4150215) 4150215..4150850 - 636 WP_003837147.1 HNH endonuclease -
NFJ16_RS19790 (4150991) 4150991..4151863 + 873 WP_048216872.1 HNH endonuclease -
NFJ16_RS19795 (4152044) 4152044..4153051 - 1008 WP_100684815.1 restriction endonuclease -
NFJ16_RS19800 (4153128) 4153128..4153958 - 831 WP_186557011.1 DUF4942 domain-containing protein -
NFJ16_RS19805 (4154072) 4154072..4154392 - 321 WP_279264317.1 TA system toxin CbtA family protein Toxin
NFJ16_RS19810 (4154429) 4154429..4154752 - 324 WP_186557010.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFJ16_RS19815 (4154765) 4154765..4155235 - 471 WP_032439573.1 DNA repair protein RadC -
NFJ16_RS19820 (4155306) 4155306..4156127 - 822 WP_186557013.1 DUF932 domain-containing protein -
NFJ16_RS19825 (4156226) 4156226..4156438 - 213 WP_032439571.1 hypothetical protein -
NFJ16_RS19830 (4156512) 4156512..4156868 - 357 WP_223366209.1 hypothetical protein -
NFJ16_RS19835 (4156941) 4156941..4157405 - 465 WP_279264318.1 hypothetical protein -
NFJ16_RS19840 (4158271) 4158271..4159725 + 1455 WP_186557004.1 YfjI family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(7-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12058.70 Da        Isoelectric Point: 6.6410

>T248343 WP_279264317.1 NZ_CP099303:c4154392-4154072 [Citrobacter freundii]
MHISTVPAKVSVSSRLSPVQVWQQLLTYLLNHHYGLTLNDTPFHDDTAIQEHIEAGIVIADAVNFLVERYELVRTDRKGF
TWQDQTPFLTATDILRARRATGLINT

Download         Length: 321 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11942.68 Da        Isoelectric Point: 6.6974

>AT248343 WP_186557010.1 NZ_CP099303:c4154752-4154429 [Citrobacter freundii]
MPFTLPHEWGLQSDITPRFGARLVQEGTRLHYLADRAGLTGEITSKQLQKLDQTFPLFISKLEAMLCSGELNSQQQHQVT
IQLASLTCIADTRGSCGYVYISIYPTP

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References