248342

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 3730201..3730907 Replicon chromosome
Accession NZ_CP099303
Organism Citrobacter freundii strain RHB02-E1-C01

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag NFJ16_RS17835 Protein ID WP_039556156.1
Coordinates 3730201..3730569 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NFJ16_RS17840 Protein ID WP_039556157.1
Coordinates 3730590..3730907 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ16_RS17820 (3725340) 3725340..3726791 + 1452 WP_003838742.1 Na+/H+ antiporter NhaC -
NFJ16_RS17825 (3726804) 3726804..3727985 + 1182 WP_003838744.1 MalY/PatB family protein -
NFJ16_RS17830 (3728151) 3728151..3729629 - 1479 WP_032941279.1 hypothetical protein -
NFJ16_RS17835 (3730201) 3730201..3730569 - 369 WP_039556156.1 TA system toxin CbtA family protein Toxin
NFJ16_RS17840 (3730590) 3730590..3730907 - 318 WP_039556157.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFJ16_RS17845 (3730926) 3730926..3731143 - 218 Protein_3494 DUF987 family protein -
NFJ16_RS17850 (3731152) 3731152..3731634 - 483 WP_039556158.1 DNA repair protein RadC -
NFJ16_RS17855 (3731643) 3731643..3732086 - 444 WP_096164809.1 antirestriction protein -
NFJ16_RS17860 (3732117) 3732117..3732938 - 822 WP_058647033.1 DUF932 domain-containing protein -
NFJ16_RS17865 (3733058) 3733058..3733531 - 474 WP_058647034.1 hypothetical protein -
NFJ16_RS17870 (3733603) 3733603..3734055 - 453 WP_089586936.1 hypothetical protein -
NFJ16_RS17875 (3734091) 3734091..3734807 - 717 WP_058647035.1 WYL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3721066..3731143 10077


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13715.99 Da        Isoelectric Point: 8.7174

>T248342 WP_039556156.1 NZ_CP099303:c3730569-3730201 [Citrobacter freundii]
MKTLPATISRATKPCLSPVAVWQMLLTRLLEQHYGLMLSDTPFSDETIIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQVQAPYLTATDILQARKACGLMSRCSYREVSNIVLSRSRL

Download         Length: 369 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11901.43 Da        Isoelectric Point: 6.6246

>AT248342 WP_039556157.1 NZ_CP099303:c3730907-3730590 [Citrobacter freundii]
MSNITWGLQRDTTPRLGARLVQEGNQLHYLADRASITGKFSDAECRKLDETFPHFISQMESMLTTGEMNPRHAHCVILYH
NGFTCEADTLGSCGYVYISVYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References