248331

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4775117..4775783 Replicon chromosome
Accession NZ_CP099298
Organism Citrobacter freundii strain RHB02-E3-C01

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag NFJ20_RS23010 Protein ID WP_086529694.1
Coordinates 4775424..4775783 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag NFJ20_RS23005 Protein ID WP_279274146.1
Coordinates 4775117..4775434 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ20_RS22970 (4770300) 4770300..4771097 + 798 WP_003841402.1 PTS mannose/fructose/sorbose transporter subunit IIC -
NFJ20_RS22975 (4771109) 4771109..4771933 + 825 WP_048216971.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
NFJ20_RS22980 (4772001) 4772001..4773224 + 1224 WP_003031639.1 L-sorbose 1-phosphate reductase -
NFJ20_RS22985 (4773226) 4773226..4774038 + 813 WP_200058921.1 shikimate 5-dehydrogenase -
NFJ20_RS22990 (4774084) 4774084..4774440 - 357 WP_200083160.1 hypothetical protein -
NFJ20_RS22995 (4774572) 4774572..4774745 + 174 WP_032938222.1 hypothetical protein -
NFJ20_RS23000 (4774816) 4774816..4774977 + 162 WP_003841416.1 phage protein -
NFJ20_RS23005 (4775117) 4775117..4775434 - 318 WP_279274146.1 helix-turn-helix transcriptional regulator Antitoxin
NFJ20_RS23010 (4775424) 4775424..4775783 - 360 WP_086529694.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFJ20_RS23015 (4775997) 4775997..4776686 + 690 WP_279274542.1 dipeptidase PepE -
NFJ20_RS23020 (4776752) 4776752..4778383 - 1632 WP_003031618.1 Na/Pi cotransporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-90)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13422.52 Da        Isoelectric Point: 10.2555

>T248331 WP_086529694.1 NZ_CP099298:c4775783-4775424 [Citrobacter freundii]
MTKPLYWVGQARKDLLAMPEHVRDTFGFALWLAQQGKQHSQTKPLKGFGGAGVLEVVEDYHGSAWRAVYTIQLKNAVYVL
HVFQKKSVSGKATPKPEIDLIYQRLKAAQRHAQESGYVI

Download         Length: 360 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11535.41 Da        Isoelectric Point: 6.3131

>AT248331 WP_279274146.1 NZ_CP099298:c4775434-4775117 [Citrobacter freundii]
MSYEVEASSGNVYVDLGAYDAEQMQLKAQLTMVIGEILQRKGLTQQQAAQLLGMTQPKLSNLLRGQFRGISEAKMLECLV
RLGRDVEIVVGEEGNMSGKLKVKFG

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References