Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2175038..2175180 Replicon chromosome
Accession NZ_CP099298
Organism Citrobacter freundii strain RHB02-E3-C01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2175073..2175176 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2175038..2175180 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ20_RS10385 2171485..2172147 - 663 WP_192468854.1 exodeoxyribonuclease X -
NFJ20_RS10390 2172171..2172827 - 657 WP_003034921.1 carbon-nitrogen hydrolase family protein -
NFJ20_RS10395 2172934..2173164 - 231 WP_003034925.1 DNA polymerase III subunit theta -
NFJ20_RS10400 2173308..2173682 + 375 WP_003841654.1 CopC domain-containing protein YobA -
NFJ20_RS10405 2173686..2174558 + 873 WP_003034931.1 copper homeostasis membrane protein CopD -
NFJ20_RS10410 2174579..2174917 + 339 WP_003034934.1 YebY family protein -
- 2175038..2175180 - 143 - - Antitoxin
- 2175073..2175176 + 104 - - Toxin
NFJ20_RS10415 2175254..2176339 - 1086 WP_019076535.1 phage integrase Arm DNA-binding domain-containing protein -
NFJ20_RS10420 2176308..2176580 - 273 WP_032170291.1 excisionase -
NFJ20_RS10425 2176644..2176886 - 243 WP_001237028.1 DUF4060 family protein -
NFJ20_RS10430 2176873..2177520 - 648 WP_019076536.1 hypothetical protein -
NFJ20_RS10435 2177513..2177857 - 345 WP_019076537.1 hypothetical protein -
NFJ20_RS10440 2177892..2178983 - 1092 WP_199981214.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2155204..2229567 74363


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T248323 NZ_CP099298:2175073-2175176 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 143 bp

>AT248323 NZ_CP099298:c2175180-2175038 [Citrobacter freundii]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References