Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 755310..756088 Replicon chromosome
Accession NZ_CP099298
Organism Citrobacter freundii strain RHB02-E3-C01

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag NFJ20_RS03650 Protein ID WP_279274257.1
Coordinates 755600..756088 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag NFJ20_RS03645 Protein ID WP_077226964.1
Coordinates 755310..755603 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ20_RS03635 (750651) 750651..752939 + 2289 WP_213749856.1 FdhF/YdeP family oxidoreductase -
NFJ20_RS03640 (753093) 753093..754952 + 1860 WP_003838200.1 bifunctional glutathionylspermidine amidase/synthase -
NFJ20_RS03645 (755310) 755310..755603 + 294 WP_077226964.1 DUF1778 domain-containing protein Antitoxin
NFJ20_RS03650 (755600) 755600..756088 + 489 WP_279274257.1 GNAT family N-acetyltransferase Toxin
NFJ20_RS03655 (756233) 756233..756736 - 504 WP_279274258.1 hypothetical protein -
NFJ20_RS03660 (756767) 756767..757018 - 252 WP_279274259.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17650.49 Da        Isoelectric Point: 8.5147

>T248319 WP_279274257.1 NZ_CP099298:755600-756088 [Citrobacter freundii]
MISAPEPLHAGHVLTSFCCGVDSMDNWLKQRAMKNQVTGASRTFVCCDNNSKVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLRGRGIGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDSMMLMVTLGDLV
HS

Download         Length: 489 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10856.46 Da        Isoelectric Point: 9.8590

>AT248319 WP_077226964.1 NZ_CP099298:755310-755603 [Citrobacter freundii]
MPAANSMAIKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPDAYQAFLARLDQAPAPN
EALRKTMQTPAPWEQNK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References