Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2231091..2231631 Replicon chromosome
Accession NC_014311
Organism Ralstonia solanacearum PSI07

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag RPSI07_RS17935 Protein ID WP_048817440.1
Coordinates 2231091..2231351 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RPSI07_RS17940 Protein ID WP_013212794.1
Coordinates 2231344..2231631 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPSI07_RS17915 2227223..2228140 - 918 WP_013212788.1 sugar ABC transporter substrate-binding protein -
RPSI07_RS17920 2228351..2229403 - 1053 WP_013212789.1 LacI family DNA-binding transcriptional regulator -
RPSI07_RS17925 2229539..2230687 + 1149 WP_013212790.1 fatty acid desaturase family protein -
RPSI07_RS17930 2230653..2230964 + 312 WP_048817439.1 Rieske 2Fe-2S domain-containing protein -
RPSI07_RS17935 2231091..2231351 + 261 WP_048817440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RPSI07_RS17940 2231344..2231631 + 288 WP_013212794.1 putative addiction module antidote protein Antitoxin
RPSI07_RS17945 2231644..2232489 - 846 WP_013212795.1 TIM barrel protein -
RPSI07_RS17950 2232486..2233523 - 1038 WP_013212796.1 hypothetical protein -
RPSI07_RS17955 2233520..2234809 - 1290 WP_013212797.1 FAD-dependent oxidoreductase -
RPSI07_RS17960 2234976..2235893 + 918 WP_013212798.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-79)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9435.79 Da        Isoelectric Point: 10.3136

>T24831 WP_048817440.1 NC_014311:2231091-2231351 [Ralstonia solanacearum PSI07]
MRDKRAKARIAARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGNKATQAQDIKQAIRMARDL
KESGHD

Download         Length: 261 bp

>T24831 NC_014311:2231091-2231351 [Ralstonia solanacearum PSI07]
CTGCGCGACAAGCGTGCCAAGGCGCGGATCGCCGCCCGGCTGGTCAGCGCATCGTTCGGGAATTTCGGCGACTGCAAGCC
GGTGGGTGAAGGCGTGAGCGAGATGCGGATCGATGTGGGCGCCGGGTATCGCGTCTACTACACGCGACAAGGTACTGTCG
TCTACATCCTGCTCACGGGCGGCAACAAGGCAACCCAAGCCCAGGACATCAAGCAAGCCATCCGGATGGCACGCGACCTG
AAGGAGTCAGGCCATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10022.45 Da        Isoelectric Point: 4.7361

>AT24831 WP_013212794.1 NC_014311:2231344-2231631 [Ralstonia solanacearum PSI07]
MTETYAPFDAAAYLDSEETIAEFLAAAMEDPNPDVFLAALGAVARARGIAKVAADAGLGRESLYKAISPGAHPRYETIQK
IMRALGVRLNVTPAA

Download         Length: 288 bp

>AT24831 NC_014311:2231344-2231631 [Ralstonia solanacearum PSI07]
ATGACTGAAACCTACGCACCGTTTGACGCGGCGGCCTACCTCGATAGCGAAGAGACCATCGCCGAATTTCTGGCGGCCGC
GATGGAAGACCCGAATCCGGATGTCTTCCTGGCTGCCCTCGGTGCCGTTGCACGCGCCCGCGGCATTGCCAAGGTGGCTG
CGGACGCGGGCCTGGGGCGCGAAAGCCTGTACAAGGCCATCAGCCCCGGCGCGCACCCGCGCTACGAAACCATCCAGAAA
ATCATGCGCGCACTGGGCGTCAGGCTGAACGTGACGCCTGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References