248284

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4463345..4463880 Replicon chromosome
Accession NZ_CP099254
Organism Citrobacter freundii strain RHB09-E3-C07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFJ59_RS21025 Protein ID WP_279277372.1
Coordinates 4463593..4463880 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFJ59_RS21020 Protein ID WP_137399198.1
Coordinates 4463345..4463596 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ59_RS20990 (4458838) 4458838..4459596 + 759 WP_182270582.1 phosphonate C-P lyase system protein PhnK -
NFJ59_RS20995 (4459703) 4459703..4460383 + 681 WP_182270583.1 phosphonate C-P lyase system protein PhnL -
NFJ59_RS21000 (4460380) 4460380..4461516 + 1137 WP_182270584.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
NFJ59_RS21005 (4461519) 4461519..4462073 + 555 WP_182270585.1 ribose 1,5-bisphosphokinase -
NFJ59_RS21010 (4462060) 4462060..4462494 + 435 WP_182270586.1 aminoalkylphosphonate N-acetyltransferase -
NFJ59_RS21015 (4462503) 4462503..4463261 + 759 WP_182270587.1 phosphonate metabolism protein PhnP -
NFJ59_RS21020 (4463345) 4463345..4463596 + 252 WP_137399198.1 antitoxin Antitoxin
NFJ59_RS21025 (4463593) 4463593..4463880 + 288 WP_279277372.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFJ59_RS21030 (4463877) 4463877..4464206 - 330 WP_279277373.1 DDRRRQL repeat protein YjdP -
NFJ59_RS21035 (4464276) 4464276..4466540 - 2265 WP_279277374.1 hybrid sensor histidine kinase/response regulator -
NFJ59_RS21040 (4466655) 4466655..4468178 + 1524 WP_279277375.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11072.98 Da        Isoelectric Point: 10.4701

>T248284 WP_279277372.1 NZ_CP099254:4463593-4463880 [Citrobacter freundii]
MSYTVKFREDALKEWQKLDKTIQQQFAKKLKKCGENPHVPSAKLRGIKDCYKIKLRTSGFRLVYQVIDDTLVIAVVAVGK
RERSEVYNLASERLR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9242.56 Da        Isoelectric Point: 4.2965

>AT248284 WP_137399198.1 NZ_CP099254:4463345-4463596 [Citrobacter freundii]
MPHIILSDTTASVSELKKNPMATVSAGDGFPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVHERNQQPLVDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References