Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 932469..933114 Replicon chromosome
Accession NZ_CP099254
Organism Citrobacter freundii strain RHB09-E3-C07

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFJ59_RS04605 Protein ID WP_181617795.1
Coordinates 932716..933114 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NFJ59_RS04600 Protein ID WP_181617796.1
Coordinates 932469..932735 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ59_RS04575 (927684) 927684..929117 - 1434 WP_181617800.1 6-phospho-beta-glucosidase BglA -
NFJ59_RS04580 (929238) 929238..929966 - 729 WP_115259901.1 MurR/RpiR family transcriptional regulator -
NFJ59_RS04585 (930019) 930019..930330 + 312 WP_279277715.1 N(4)-acetylcytidine aminohydrolase -
NFJ59_RS04590 (930494) 930494..931153 + 660 WP_096755796.1 hemolysin III family protein -
NFJ59_RS04595 (931233) 931233..932213 - 981 WP_181617797.1 tRNA-modifying protein YgfZ -
NFJ59_RS04600 (932469) 932469..932735 + 267 WP_181617796.1 FAD assembly factor SdhE Antitoxin
NFJ59_RS04605 (932716) 932716..933114 + 399 WP_181617795.1 protein YgfX Toxin
NFJ59_RS04610 (933160) 933160..933681 - 522 WP_181617794.1 flavodoxin FldB -
NFJ59_RS04615 (933794) 933794..934690 + 897 WP_181617793.1 site-specific tyrosine recombinase XerD -
NFJ59_RS04620 (934714) 934714..935427 + 714 WP_181617792.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFJ59_RS04625 (935433) 935433..937166 + 1734 WP_279277716.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15634.57 Da        Isoelectric Point: 11.2851

>T248275 WP_181617795.1 NZ_CP099254:932716-933114 [Citrobacter freundii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWTIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQQK

Download         Length: 399 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10628.14 Da        Isoelectric Point: 5.1599

>AT248275 WP_181617796.1 NZ_CP099254:932469-932735 [Citrobacter freundii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References