Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 61912..62522 Replicon plasmid mpPSI07
Accession NC_014310
Organism Ralstonia solanacearum PSI07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RPSI07_RS00275 Protein ID WP_013209164.1
Coordinates 62214..62522 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RPSI07_RS00270 Protein ID WP_013209163.1
Coordinates 61912..62217 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPSI07_RS00245 57880..58290 + 411 WP_013209158.1 acyl-CoA thioesterase -
RPSI07_RS00250 58328..58720 + 393 WP_013209159.1 RidA family protein -
RPSI07_RS00255 59035..59316 - 282 WP_013209160.1 hypothetical protein -
RPSI07_RS00260 59449..59733 - 285 WP_013209161.1 hypothetical protein -
RPSI07_RS25395 60067..60183 + 117 Protein_54 IS5/IS1182 family transposase -
RPSI07_RS00265 60388..61701 - 1314 WP_013209162.1 metabolite/H+ symporter -
RPSI07_RS00270 61912..62217 - 306 WP_013209163.1 putative addiction module antidote protein Antitoxin
RPSI07_RS00275 62214..62522 - 309 WP_013209164.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RPSI07_RS00280 62607..63806 - 1200 WP_013209165.1 MFS transporter -
RPSI07_RS00285 63934..64749 - 816 WP_013209166.1 GntR family transcriptional regulator -
RPSI07_RS00290 64923..65474 - 552 WP_048816929.1 helix-turn-helix transcriptional regulator -
RPSI07_RS00295 65606..66202 + 597 WP_013209168.1 GNAT family N-acetyltransferase -
RPSI07_RS00300 66465..66899 + 435 WP_013209169.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgC / flgG / fliM / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2085000 2085000


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11791.53 Da        Isoelectric Point: 9.0017

>T24827 WP_013209164.1 NC_014310:c62522-62214 [Ralstonia solanacearum PSI07]
MLTIRTTEIFDDWFYSLRDKAAQRRVQVRIDRLQMGNPGDVKAVREGIREMRIDHGPGYRVYVAQRGVVLIVLLCGGDKS
TQEADVRRAIDLSRRLDVDNME

Download         Length: 309 bp

>T24827 NC_014310:c62522-62214 [Ralstonia solanacearum PSI07]
ATGCTGACAATCCGCACGACTGAAATCTTCGACGACTGGTTTTACAGTCTCCGCGACAAGGCCGCGCAACGCCGCGTCCA
GGTGCGCATCGATCGCCTGCAGATGGGCAATCCAGGCGATGTGAAAGCTGTACGTGAAGGCATCCGTGAGATGCGGATCG
ATCATGGCCCGGGCTATCGCGTGTATGTTGCACAGCGTGGCGTGGTCCTGATCGTCCTGCTGTGCGGCGGTGACAAGTCG
ACGCAGGAAGCCGATGTCCGCCGCGCAATCGACCTGTCCCGCCGTCTTGACGTGGACAACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11009.67 Da        Isoelectric Point: 6.7174

>AT24827 WP_013209163.1 NC_014310:c62217-61912 [Ralstonia solanacearum PSI07]
MMMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARARGMTQIARETGMTREGLYKALSEDGNP
SFATVLKVIRALGIRLHAVPA

Download         Length: 306 bp

>AT24827 NC_014310:c62217-61912 [Ralstonia solanacearum PSI07]
ATGATGATGGCCCAACGCACCATAAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTATCTCGACGCCTGCCTGGAGGAAGCCGGGGATGACCCCGCATTCATCACGCACGCGCTGGGCGTGGTCGCGCGGGCGC
GCGGCATGACGCAGATCGCCCGCGAGACCGGGATGACGCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGACGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References