Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1115982..1116701 Replicon chromosome
Accession NZ_CP099222
Organism Citrobacter freundii strain RHB13-SO-C05

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NFJ76_RS05345 Protein ID WP_131000374.1
Coordinates 1115982..1116302 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NFJ76_RS05350 Protein ID WP_131000373.1
Coordinates 1116336..1116701 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ76_RS05330 (1111856) 1111856..1113760 + 1905 WP_115257695.1 5-dehydro-2-deoxygluconokinase -
NFJ76_RS05335 (1113775) 1113775..1114665 + 891 WP_096756056.1 myo-inosose-2 dehydratase -
NFJ76_RS05340 (1114675) 1114675..1115493 + 819 WP_181506668.1 5-deoxy-glucuronate isomerase -
NFJ76_RS05345 (1115982) 1115982..1116302 - 321 WP_131000374.1 TA system toxin CbtA family protein Toxin
NFJ76_RS05350 (1116336) 1116336..1116701 - 366 WP_131000373.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NFJ76_RS05355 (1116733) 1116733..1116954 - 222 WP_131000372.1 DUF987 domain-containing protein -
NFJ76_RS05360 (1116963) 1116963..1117433 - 471 WP_279271638.1 DNA repair protein RadC -
NFJ76_RS05365 (1117500) 1117500..1118321 - 822 WP_131000370.1 DUF932 domain-containing protein -
NFJ76_RS05370 (1118389) 1118389..1118841 - 453 WP_131000369.1 hypothetical protein -
NFJ76_RS05375 (1119085) 1119085..1119888 - 804 WP_131000367.1 hypothetical protein -
NFJ76_RS05380 (1119908) 1119908..1120342 - 435 WP_117037059.1 hypothetical protein -
NFJ76_RS05385 (1120925) 1120925..1121560 + 636 WP_181212972.1 inovirus Gp2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1030655..1191497 160842


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(18-116)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12149.85 Da        Isoelectric Point: 6.2084

>T248249 WP_131000374.1 NZ_CP099222:c1116302-1115982 [Citrobacter freundii]
MHISTVPVTVPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDSAIQEHIEAGITLADAVNFLVERYELVRIDRKGF
TWQEQTPFLTTIDLLRARRATGLVHT

Download         Length: 321 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13510.18 Da        Isoelectric Point: 6.3176

>AT248249 WP_131000373.1 NZ_CP099222:c1116701-1116336 [Citrobacter freundii]
MQSTTLSGSSAENTSCLQWGLKRNITPCFDARLVQEGNRLYFLADRAGFNGSFSDDEALRLDQVFPLMMKHLERMLTTGE
LDPRSQHSVTLHHNGLTCEADTLGSHGYVYIAIYPQSAVTR

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References