Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 817020..817674 Replicon chromosome
Accession NZ_CP099222
Organism Citrobacter freundii strain RHB13-SO-C05

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFJ76_RS03995 Protein ID WP_096755799.1
Coordinates 817267..817674 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NFJ76_RS03990 Protein ID WP_279271574.1
Coordinates 817020..817286 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ76_RS03965 (812228) 812228..813667 - 1440 WP_181637573.1 6-phospho-beta-glucosidase BglA -
NFJ76_RS03970 (813788) 813788..814516 - 729 WP_115259901.1 MurR/RpiR family transcriptional regulator -
NFJ76_RS03975 (814569) 814569..814880 + 312 WP_279271573.1 N(4)-acetylcytidine aminohydrolase -
NFJ76_RS03980 (815044) 815044..815703 + 660 WP_096755796.1 hemolysin III family protein -
NFJ76_RS03985 (815783) 815783..816763 - 981 WP_115257540.1 tRNA-modifying protein YgfZ -
NFJ76_RS03990 (817020) 817020..817286 + 267 WP_279271574.1 FAD assembly factor SdhE Antitoxin
NFJ76_RS03995 (817267) 817267..817674 + 408 WP_096755799.1 protein YgfX Toxin
NFJ76_RS04000 (817720) 817720..818241 - 522 WP_279271575.1 flavodoxin FldB -
NFJ76_RS04005 (818354) 818354..819250 + 897 WP_096755801.1 site-specific tyrosine recombinase XerD -
NFJ76_RS04010 (819274) 819274..819987 + 714 WP_096755802.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFJ76_RS04015 (819993) 819993..821726 + 1734 WP_181631884.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15935.93 Da        Isoelectric Point: 11.2851

>T248248 WP_096755799.1 NZ_CP099222:817267-817674 [Citrobacter freundii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10600.13 Da        Isoelectric Point: 5.6311

>AT248248 WP_279271574.1 NZ_CP099222:817020-817286 [Citrobacter freundii]
MDINNKTRIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References