Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2162041..2162181 Replicon chromosome
Accession NZ_CP099217
Organism Citrobacter freundii strain RHB16-SO-C03

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2162076..2162179 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2162041..2162181 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFJ87_RS10500 2158488..2159150 - 663 WP_003833802.1 exodeoxyribonuclease X -
NFJ87_RS10505 2159174..2159830 - 657 WP_003841657.1 carbon-nitrogen hydrolase family protein -
NFJ87_RS10510 2159937..2160167 - 231 WP_003034925.1 DNA polymerase III subunit theta -
NFJ87_RS10515 2160311..2160685 + 375 WP_003034928.1 CopC domain-containing protein YobA -
NFJ87_RS10520 2160689..2161561 + 873 WP_003034931.1 copper homeostasis membrane protein CopD -
NFJ87_RS10525 2161582..2161920 + 339 WP_279270803.1 YebY family protein -
- 2162041..2162181 - 141 - - Antitoxin
- 2162076..2162179 + 104 - - Toxin
NFJ87_RS10530 2162257..2163342 - 1086 WP_279270804.1 phage integrase Arm DNA-binding domain-containing protein -
NFJ87_RS10535 2163311..2163583 - 273 WP_199950439.1 excisionase -
NFJ87_RS10540 2163648..2163890 - 243 WP_005121071.1 DUF4060 family protein -
NFJ87_RS10545 2163930..2165015 - 1086 WP_038641385.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2156419..2217978 61559


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T248234 NZ_CP099217:2162076-2162179 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT248234 NZ_CP099217:c2162181-2162041 [Citrobacter freundii]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References