Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1908117..1908262 Replicon chromosome
Accession NZ_CP099140
Organism Klebsiella pneumoniae strain RHB28-SO-C05

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1908153..1908255 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1908117..1908262 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK38_RS09280 (NFK38_09270) 1903247..1905307 + 2061 WP_019705169.1 oligopeptidase B -
NFK38_RS09285 (NFK38_09275) 1905311..1905970 - 660 WP_002911407.1 exodeoxyribonuclease X -
NFK38_RS09290 (NFK38_09280) 1906049..1906279 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NFK38_RS09295 (NFK38_09285) 1906392..1906766 + 375 WP_014343244.1 CopC domain-containing protein YobA -
NFK38_RS09300 (NFK38_09290) 1906770..1907639 + 870 WP_014343243.1 copper homeostasis membrane protein CopD -
NFK38_RS09305 (NFK38_09295) 1907656..1907994 + 339 WP_002911404.1 YebY family protein -
- 1908117..1908262 - 146 - - Antitoxin
- 1908153..1908255 + 103 - - Toxin
NFK38_RS09310 (NFK38_09300) 1908630..1908773 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NFK38_RS09315 (NFK38_09305) 1908878..1909846 - 969 WP_004151446.1 VirK/YbjX family protein -
NFK38_RS09320 (NFK38_09310) 1910003..1910656 + 654 WP_014343242.1 protein-serine/threonine phosphatase -
NFK38_RS09325 (NFK38_09315) 1910653..1910844 - 192 WP_002911395.1 YebW family protein -
NFK38_RS09330 (NFK38_09320) 1910942..1911181 - 240 WP_002911393.1 YebV family protein -
NFK38_RS09335 (NFK38_09325) 1911297..1912730 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T248218 NZ_CP099140:1908153-1908255 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT248218 NZ_CP099140:c1908262-1908117 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References