Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3885318..3885972 Replicon chromosome
Accession NZ_CP099084
Organism Citrobacter freundii strain RHB43-C17

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NFK79_RS18700 Protein ID WP_096755799.1
Coordinates 3885318..3885725 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NFK79_RS18705 Protein ID WP_096755798.1
Coordinates 3885706..3885972 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK79_RS18680 (3881266) 3881266..3882999 - 1734 WP_096755803.1 single-stranded-DNA-specific exonuclease RecJ -
NFK79_RS18685 (3883005) 3883005..3883718 - 714 WP_096755802.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFK79_RS18690 (3883742) 3883742..3884638 - 897 WP_096755801.1 site-specific tyrosine recombinase XerD -
NFK79_RS18695 (3884751) 3884751..3885272 + 522 WP_096755800.1 flavodoxin FldB -
NFK79_RS18700 (3885318) 3885318..3885725 - 408 WP_096755799.1 protein YgfX Toxin
NFK79_RS18705 (3885706) 3885706..3885972 - 267 WP_096755798.1 FAD assembly factor SdhE Antitoxin
NFK79_RS18710 (3886229) 3886229..3887209 + 981 WP_096755797.1 tRNA-modifying protein YgfZ -
NFK79_RS18715 (3887289) 3887289..3887948 - 660 WP_096755796.1 hemolysin III family protein -
NFK79_RS18720 (3888112) 3888112..3888423 - 312 WP_096755795.1 N(4)-acetylcytidine aminohydrolase -
NFK79_RS18725 (3888476) 3888476..3889204 + 729 WP_115259901.1 MurR/RpiR family transcriptional regulator -
NFK79_RS18730 (3889325) 3889325..3890758 + 1434 WP_181498593.1 6-phospho-beta-glucosidase BglA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-131)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 136 a.a.        Molecular weight: 15935.93 Da        Isoelectric Point: 11.2851

>T248196 WP_096755799.1 NZ_CP099084:c3885725-3885318 [Citrobacter freundii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10570.10 Da        Isoelectric Point: 5.6311

>AT248196 WP_096755798.1 NZ_CP099084:c3885972-3885706 [Citrobacter freundii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References