Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 598924..599440 Replicon chromosome
Accession NZ_CP099084
Organism Citrobacter freundii strain RHB43-C17

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NFK79_RS02955 Protein ID WP_096758513.1
Coordinates 599156..599440 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NFK79_RS02950 Protein ID WP_096758514.1
Coordinates 598924..599166 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFK79_RS02930 (593939) 593939..595072 + 1134 WP_181498907.1 amidohydrolase/deacetylase family metallohydrolase -
NFK79_RS02935 (595056) 595056..596174 + 1119 WP_181498908.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
NFK79_RS02940 (596171) 596171..596911 + 741 WP_096758516.1 KDGP aldolase family protein -
NFK79_RS02945 (596933) 596933..598846 + 1914 WP_181498909.1 BglG family transcription antiterminator -
NFK79_RS02950 (598924) 598924..599166 + 243 WP_096758514.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NFK79_RS02955 (599156) 599156..599440 + 285 WP_096758513.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NFK79_RS02960 (599444) 599444..599908 - 465 WP_181498910.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NFK79_RS02965 (599909) 599909..600223 - 315 WP_181498911.1 hypothetical protein -
NFK79_RS02970 (600339) 600339..602477 - 2139 WP_096758512.1 anaerobic ribonucleoside-triphosphate reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10815.65 Da        Isoelectric Point: 9.6730

>T248186 WP_096758513.1 NZ_CP099084:599156-599440 [Citrobacter freundii]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSACLNGLPDCYKIKLKSSGYRLVYQVRDEVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0490

>AT248186 WP_096758514.1 NZ_CP099084:598924-599166 [Citrobacter freundii]
MATLNVRLDDKLKNEAYAVLDKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKISLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References