Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 458164..458942 | Replicon | chromosome |
Accession | NZ_CP099084 | ||
Organism | Citrobacter freundii strain RHB43-C17 |
Toxin (Protein)
Gene name | TacT2 | Uniprot ID | - |
Locus tag | NFK79_RS02240 | Protein ID | WP_279264552.1 |
Coordinates | 458454..458942 (+) | Length | 163 a.a. |
Antitoxin (Protein)
Gene name | TacA2 | Uniprot ID | - |
Locus tag | NFK79_RS02235 | Protein ID | WP_096758633.1 |
Coordinates | 458164..458457 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NFK79_RS02230 (454236) | 454236..457496 | + | 3261 | WP_279264551.1 | peroxidase family protein | - |
NFK79_RS02235 (458164) | 458164..458457 | + | 294 | WP_096758633.1 | DUF1778 domain-containing protein | Antitoxin |
NFK79_RS02240 (458454) | 458454..458942 | + | 489 | WP_279264552.1 | GNAT family N-acetyltransferase | Toxin |
NFK79_RS02245 (459227) | 459227..459406 | - | 180 | Protein_440 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
NFK79_RS02250 (460374) | 460374..461714 | - | 1341 | WP_279264553.1 | hypothetical protein | - |
NFK79_RS02255 (461792) | 461792..462685 | - | 894 | Protein_442 | IS3 family transposase | - |
NFK79_RS02260 (462698) | 462698..463849 | - | 1152 | WP_112150722.1 | IS30 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 458164..470557 | 12393 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 163 a.a. Molecular weight: 17587.57 Da Isoelectric Point: 7.7294
>T248185 WP_279264552.1 NZ_CP099084:458454-458942 [Citrobacter freundii]
MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQLSGASRTFVCCDDVKVMAYYSLASSAVTTNTAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGLGRALMRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPLMLMVTLGDLVG
SV
MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQLSGASRTFVCCDDVKVMAYYSLASSAVTTNTAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGLGRALMRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPLMLMVTLGDLVG
SV
Download Length: 489 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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