Detailed information of TA system TA024818

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 470447..471100
• Replicon: chromosome
• Accession: NC_014259
• Organism: Acinetobacter oleivorans DR1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: AOLE_RS02270
• Protein ID: WP_035332235.1
• Coordinates: 470711..471100 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9QPI6
• Locus tag: AOLE_RS02265
• Protein ID: WP_005301304.1
• Coordinates: 470447..470704 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AOLE_RS02245	465958..466965	+	1008	WP_003653641.1	DNA-directed RNA polymerase subunit alpha	-
AOLE_RS02250	466984..467361	+	378	WP_002049717.1	50S ribosomal protein L17	-
AOLE_RS02255	467543..469033	+	1491	WP_013196781.1	NAD(P)/FAD-dependent oxidoreductase	-
AOLE_RS02260	469085..470257	-	1173	WP_013196782.1	acyl-CoA dehydrogenase family protein	-
AOLE_RS02265	470447..470704	+	258	WP_005301304.1	succinate dehydrogenase assembly factor 2	Antitoxin
AOLE_RS02270	470711..471100	+	390	WP_035332235.1	hypothetical protein	Toxin
AOLE_RS02275	471870..472958	+	1089	WP_013196784.1	hypothetical protein	-
AOLE_RS02280	473042..473617	+	576	WP_004789598.1	rhombosortase	-
AOLE_RS02285	473795..475990	+	2196	WP_013196785.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15569.01 Da
• Isoelectric Point: 10.1638

>T24818 WP_035332235.1 NC_014259:470711-471100 [Acinetobacter oleivorans DR1]
MIKELNFELKYSRFSIIFQLFIGLCLVILLYQLLPPMWWLFSLILLSIAFLLFLKQSRISQIAYLDQKSWSVVYLPKKVI
HRVEINKIIDYQLFMVVYFEGAPVKVAIIWFDQLPLQYWKKLKVLQKLH

Nucleotide

• Length: 390 bp

>T24818 NC_014259:470711-471100 [Acinetobacter oleivorans DR1]
TTGATAAAAGAATTGAATTTTGAGCTGAAATATAGTCGTTTCTCGATAATATTTCAGCTTTTTATTGGCTTGTGTTTAGT
AATCCTACTTTATCAATTGTTACCACCTATGTGGTGGTTATTTAGTCTGATCCTTTTATCTATTGCTTTCCTATTGTTTT
TAAAACAATCACGAATTTCTCAAATTGCATATTTAGATCAAAAATCTTGGTCAGTTGTTTATCTTCCTAAAAAAGTGATT
CACCGTGTAGAAATTAATAAAATAATTGATTATCAGCTATTTATGGTTGTTTATTTTGAGGGAGCACCTGTGAAAGTAGC
CATAATCTGGTTTGATCAACTTCCTTTACAGTATTGGAAAAAGTTAAAAGTCCTACAGAAACTTCATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10282.69 Da
• Isoelectric Point: 4.3805

>AT24818 WP_005301304.1 NC_014259:470447-470704 [Acinetobacter oleivorans DR1]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLTADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Nucleotide

• Length: 258 bp

>AT24818 NC_014259:470447-470704 [Acinetobacter oleivorans DR1]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCTTATGTAAAAAACTATTATCTAACTGCGGATCCGGCAGAGAAGGCCTTATTTGCAGAATTAGTCGAACAAGAAG
ATCCAGATTTGCTAGATTGGTTCATGGAAGTTTCTGAACCTCCACGCACAGAGTTACGTGAATTTATTTATAAATTAAAA
CAGTACGTACATGGCTAA

Structures

Antitoxin

• AlphaFold DB: N9QPI6