Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4041645..4042192 Replicon chromosome
Accession NZ_CP098926
Organism Halomonas sp. MS1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF683_RS18705 Protein ID WP_253920697.1
Coordinates 4041645..4041947 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NF683_RS18710 Protein ID WP_095603088.1
Coordinates 4041935..4042192 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF683_RS18670 (NF683_18665) 4036848..4037336 - 489 WP_253920692.1 VOC family protein -
NF683_RS18675 (NF683_18670) 4037488..4038279 - 792 WP_253920693.1 type I methionyl aminopeptidase -
NF683_RS18680 (NF683_18675) 4038272..4038478 - 207 WP_038485042.1 ParD-like family protein -
NF683_RS18685 (NF683_18680) 4038619..4039038 - 420 WP_253920694.1 DUF2784 domain-containing protein -
NF683_RS18690 (NF683_18685) 4039061..4040275 - 1215 WP_089040879.1 crosslink repair DNA glycosylase YcaQ family protein -
NF683_RS18695 (NF683_18690) 4040368..4040772 - 405 WP_253920695.1 DUF1801 domain-containing protein -
NF683_RS18700 (NF683_18695) 4040856..4041443 - 588 WP_253920696.1 O-methyltransferase -
NF683_RS18705 (NF683_18700) 4041645..4041947 - 303 WP_253920697.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF683_RS18710 (NF683_18705) 4041935..4042192 - 258 WP_095603088.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF683_RS18715 (NF683_18710) 4042371..4042457 - 87 Protein_3672 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
NF683_RS18720 (NF683_18715) 4042551..4043372 + 822 WP_253921906.1 aldo/keto reductase -
NF683_RS18725 (NF683_18720) 4043563..4044468 - 906 WP_253920698.1 EamA family transporter -
NF683_RS18730 (NF683_18725) 4044637..4045518 + 882 WP_022520598.1 helix-turn-helix domain-containing protein -
NF683_RS18735 (NF683_18730) 4045540..4045932 - 393 WP_193084979.1 N-acetyltransferase -
NF683_RS18740 (NF683_18735) 4045979..4046860 - 882 WP_253920699.1 DMT family transporter -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11609.31 Da        Isoelectric Point: 4.4400

>T248171 WP_253920697.1 NZ_CP098926:c4041947-4041645 [Halomonas sp. MS1]
MAEVIWTEPALQELDAIAEYIALDNPAAASHLVKDVFDKTERLENFPQSGRVPPELPNSVYREIVVLPCRIFYREDEKQV
LVLYVMREERQLRAYMLGNS

Download         Length: 303 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9887.46 Da        Isoelectric Point: 9.5103

>AT248171 WP_095603088.1 NZ_CP098926:c4042192-4041935 [Halomonas sp. MS1]
MKVELVTNLKRQATKILADLHLSKEPVLITEHGKPSAYLVDVQDYEFMQRRLELLEGLSRGERAVLEGRTYSQSEAREKM
SKWLK

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References