Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 2459052..2459599 Replicon chromosome
Accession NZ_CP098926
Organism Halomonas sp. MS1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NF683_RS11195 Protein ID WP_089039028.1
Coordinates 2459052..2459351 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NF683_RS11200 Protein ID WP_089039027.1
Coordinates 2459351..2459599 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF683_RS11170 (NF683_11165) 2454794..2456020 - 1227 WP_089039032.1 pyridoxal phosphate-dependent aminotransferase -
NF683_RS11175 (NF683_11170) 2456143..2457009 + 867 WP_089039031.1 LysR family transcriptional regulator -
NF683_RS11180 (NF683_11175) 2457100..2457864 + 765 WP_089039030.1 CPBP family intramembrane metalloprotease -
NF683_RS11185 (NF683_11180) 2457889..2458488 + 600 WP_089039029.1 lysozyme inhibitor LprI family protein -
NF683_RS11190 (NF683_11185) 2458608..2458949 - 342 WP_232471505.1 hypothetical protein -
NF683_RS11195 (NF683_11190) 2459052..2459351 - 300 WP_089039028.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF683_RS11200 (NF683_11195) 2459351..2459599 - 249 WP_089039027.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NF683_RS11205 (NF683_11200) 2459750..2460883 + 1134 WP_089039026.1 Fic family protein -
NF683_RS11210 (NF683_11205) 2461031..2461981 + 951 WP_089039025.1 DUF808 domain-containing protein -
NF683_RS11215 (NF683_11210) 2462165..2463358 - 1194 WP_198361514.1 CmlA/FloR family chloramphenicol efflux MFS transporter -
NF683_RS11220 (NF683_11215) 2463616..2464407 - 792 WP_089039023.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11927.52 Da        Isoelectric Point: 8.0469

>T248170 WP_089039028.1 NZ_CP098926:c2459351-2459052 [Halomonas sp. MS1]
MLSFRITPRARDDLKNIGRYTEWQWGKNQRNTYLKNFEKRFHWLAENPQLGKHRSDVSEGYYSYSQGQHVIFYLIGQECI
EIIGIPHKEMDIVSYFLPE

Download         Length: 300 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9134.07 Da        Isoelectric Point: 4.3875

>AT248170 WP_089039027.1 NZ_CP098926:c2459599-2459351 [Halomonas sp. MS1]
MATTSLSLGEHWEVFIRNEVSSGRYGSASEVVRDALRAMEERKSKLEALRTHLAQGAEQARTGEFVDDFSMDALINDLDS
ET

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References