Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1325710..1326620 Replicon chromosome
Accession NZ_CP098926
Organism Halomonas sp. MS1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NF683_RS05895 Protein ID WP_253921541.1
Coordinates 1326156..1326620 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NF683_RS05890 Protein ID WP_089040343.1
Coordinates 1325710..1326159 (+) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF683_RS05870 (NF683_05865) 1321814..1322782 + 969 WP_089040347.1 zinc ABC transporter substrate-binding protein -
NF683_RS05875 (NF683_05870) 1322806..1323588 + 783 WP_089040346.1 ABC transporter ATP-binding protein -
NF683_RS05880 (NF683_05875) 1323592..1324686 + 1095 WP_253921539.1 metal ABC transporter permease -
NF683_RS05885 (NF683_05880) 1324683..1325603 + 921 WP_253921540.1 metal ABC transporter permease -
NF683_RS05890 (NF683_05885) 1325710..1326159 + 450 WP_089040343.1 DUF2384 domain-containing protein Antitoxin
NF683_RS05895 (NF683_05890) 1326156..1326620 + 465 WP_253921541.1 RES family NAD+ phosphorylase Toxin
NF683_RS05900 (NF683_05895) 1326741..1327364 - 624 WP_089040341.1 TetR/AcrR family transcriptional regulator -
NF683_RS05905 (NF683_05900) 1327596..1329392 + 1797 WP_089040340.1 ABC transporter ATP-binding protein -
NF683_RS05910 (NF683_05905) 1329386..1331155 + 1770 WP_089040339.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(7-149)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(96-146)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 16935.18 Da        Isoelectric Point: 4.3319

>T248168 WP_253921541.1 NZ_CP098926:1326156-1326620 [Halomonas sp. MS1]
VNEVNAYRLIKRKYQDNAFDGEGARLYGGRWNSPGKACVYVASAESLALLEIMVHLESYQLLNAYALLRLTLPADSILGV
GEADLPDNWREAPAPAETAELGDGWLDSGHSLALAIPSVVVPREFNYMLNPEHPLFDQVITTAEALPFQPDPKL

Download         Length: 465 bp

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16695.22 Da        Isoelectric Point: 10.1982

>AT248168 WP_089040343.1 NZ_CP098926:1325710-1326159 [Halomonas sp. MS1]
MDMHFTQYQPPKALASGFWHQIGLPARGRKLHELLHQGIEYRVYPRLAKASGIEQKALAGYVDIPPATLSRRAKSGRFKM
AESDRLYRFAELFKAALDLFEGDVEGARTWLLKPNTGLGGRRPIEMSATSAEYQTVLNLIGRLEHGVAT

Download         Length: 450 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References