Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 885283..885943 Replicon chromosome
Accession NZ_CP098829
Organism Salmonella enterica subsp. enterica serovar Indiana strain YZ20MCS6

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag NFG92_RS04355 Protein ID WP_000244755.1
Coordinates 885530..885943 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NFG92_RS04350 Protein ID WP_000351186.1
Coordinates 885283..885549 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFG92_RS04330 (881592) 881592..881903 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NFG92_RS04335 (882067) 882067..882726 + 660 WP_000250289.1 hemolysin III family protein -
NFG92_RS04340 (882984) 882984..883970 + 987 WP_023226548.1 IS110 family transposase -
NFG92_RS04345 (884053) 884053..885033 - 981 WP_017441090.1 tRNA-modifying protein YgfZ -
NFG92_RS04350 (885283) 885283..885549 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NFG92_RS04355 (885530) 885530..885943 + 414 WP_000244755.1 protein YgfX Toxin
NFG92_RS04360 (885996) 885996..886517 - 522 WP_001055885.1 flavodoxin FldB -
NFG92_RS04365 (886630) 886630..887526 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NFG92_RS04370 (887550) 887550..888263 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NFG92_RS04375 (888269) 888269..890002 + 1734 WP_023227724.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T248115 WP_000244755.1 NZ_CP098829:885530-885943 [Salmonella enterica subsp. enterica serovar Indiana]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT248115 WP_000351186.1 NZ_CP098829:885283-885549 [Salmonella enterica subsp. enterica serovar Indiana]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References