Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 4464673..4465268 Replicon chromosome
Accession NZ_CP098806
Organism Dyadobacter fanqingshengii strain CY399

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NFI81_RS18525 Protein ID WP_234610996.1
Coordinates 4464882..4465268 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NFI81_RS18520 Protein ID WP_234610997.1
Coordinates 4464673..4464885 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFI81_RS18505 (NFI81_18490) 4459992..4461740 - 1749 WP_234611000.1 response regulator -
NFI81_RS18510 (NFI81_18495) 4461878..4463275 - 1398 WP_234610999.1 dihydrolipoyl dehydrogenase -
NFI81_RS18515 (NFI81_18500) 4463497..4464571 + 1075 WP_234610998.1 peptide chain release factor 2 -
NFI81_RS18520 (NFI81_18505) 4464673..4464885 + 213 WP_234610997.1 DUF2281 domain-containing protein Antitoxin
NFI81_RS18525 (NFI81_18510) 4464882..4465268 + 387 WP_234610996.1 type II toxin-antitoxin system VapC family toxin Toxin
NFI81_RS18530 (NFI81_18515) 4465268..4466056 + 789 WP_234610995.1 alpha/beta hydrolase -
NFI81_RS18535 (NFI81_18520) 4466080..4467369 + 1290 WP_234610994.1 MFS transporter -
NFI81_RS18540 (NFI81_18525) 4467450..4467884 + 435 WP_234610993.1 DoxX family protein -
NFI81_RS18545 (NFI81_18530) 4467888..4468763 - 876 WP_234610992.1 AraC family transcriptional regulator -
NFI81_RS18550 (NFI81_18535) 4468920..4469252 - 333 WP_234610991.1 RNA polymerase subunit sigma-24 -
NFI81_RS18555 (NFI81_18540) 4469282..4470253 - 972 WP_234610990.1 dihydrodipicolinate synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-119)

Antitoxin

Domain of unknown function DUF2281

(5-68)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14860.32 Da        Isoelectric Point: 5.0944

>T248107 WP_234610996.1 NZ_CP098806:4464882-4465268 [Dyadobacter fanqingshengii]
MNIILDTHTLIWFFEGDANLSAKALQAIENTENKKYVSIASLWEMAIKISLGKLYLQKPLDIFLSDLIKSDIEVLQISIA
HVLQVSQLEFFHKDPFDRIIVAQAITEQFWIVTKDPNFPLYHPFNVLW

Download         Length: 387 bp

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8168.43 Da        Isoelectric Point: 4.4354

>AT248107 WP_234610997.1 NZ_CP098806:4464673-4464885 [Dyadobacter fanqingshengii]
MTETELMKKVSVLPENLKEEVSDYVDFLISKYLHNEGSPKTPLKFGMMKGTFKMSPDFDEPLDDFKEYMP

Download         Length: 213 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References