Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/MazF(antitoxin)
Location 1815612..1816117 Replicon chromosome
Accession NZ_CP098806
Organism Dyadobacter fanqingshengii strain CY399

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NFI81_RS07390 Protein ID WP_234613163.1
Coordinates 1815926..1816117 (-) Length 64 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NFI81_RS07385 Protein ID WP_234613164.1
Coordinates 1815612..1815932 (-) Length 107 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFI81_RS07370 (NFI81_07365) 1812067..1813467 - 1401 WP_234613167.1 pyridoxal-dependent decarboxylase -
NFI81_RS07375 (NFI81_07370) 1813488..1813961 - 474 WP_234613166.1 DUF1572 family protein -
NFI81_RS07380 (NFI81_07375) 1814170..1815615 + 1446 WP_234613165.1 PLP-dependent aminotransferase family protein -
NFI81_RS07385 (NFI81_07380) 1815612..1815932 - 321 WP_234613164.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
NFI81_RS07390 (NFI81_07385) 1815926..1816117 - 192 WP_234613163.1 hypothetical protein Toxin
NFI81_RS07395 (NFI81_07390) 1816423..1818435 + 2013 WP_234613161.1 heavy metal translocating P-type ATPase -
NFI81_RS07400 (NFI81_07395) 1818453..1818773 + 321 WP_234613160.1 hypothetical protein -
NFI81_RS07405 (NFI81_07400) 1818818..1820788 + 1971 WP_234613159.1 TonB-dependent receptor plug domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(4-105)


Sequences


Toxin        


Download         Length: 64 a.a.        Molecular weight: 7223.96 Da        Isoelectric Point: 3.7677

>T248106 WP_234613163.1 NZ_CP098806:c1816117-1815926 [Dyadobacter fanqingshengii]
MMEQCDIKDLVNVEVKGNAIVIEPATQSPRAGWEQQFELAKKGSEEDLMEGFSNDFDDSEWTW

Download         Length: 192 bp


Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11682.81 Da        Isoelectric Point: 9.9469

>AT248106 WP_234613164.1 NZ_CP098806:c1815932-1815612 [Dyadobacter fanqingshengii]
MVIKRFEIYFVSLDPTIGSEIKKSRPCVVISPDEMNRSLNTVIVAPLTSTMKKYPTRINCTVASKSGQIALDQLRTVDKV
RLSKKIAVLDADTADGVLDILKALFA

Download         Length: 321 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References