Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 4248049..4248641 Replicon chromosome
Accession NZ_CP098805
Organism Dyadobacter chenhuakuii strain CY22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NFI80_RS17565 Protein ID WP_235165538.1
Coordinates 4248258..4248641 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NFI80_RS17560 Protein ID WP_235165537.1
Coordinates 4248049..4248261 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFI80_RS17545 (NFI80_17545) 4243306..4245063 - 1758 WP_235165535.1 response regulator -
NFI80_RS17550 (NFI80_17550) 4245200..4246597 - 1398 WP_233794784.1 dihydrolipoyl dehydrogenase -
NFI80_RS17555 (NFI80_17555) 4246876..4247950 + 1075 WP_157486611.1 peptide chain release factor 2 -
NFI80_RS17560 (NFI80_17560) 4248049..4248261 + 213 WP_235165537.1 DUF2281 domain-containing protein Antitoxin
NFI80_RS17565 (NFI80_17565) 4248258..4248641 + 384 WP_235165538.1 type II toxin-antitoxin system VapC family toxin Toxin
NFI80_RS17570 (NFI80_17570) 4248641..4249429 + 789 WP_235165540.1 alpha/beta hydrolase -
NFI80_RS17575 (NFI80_17575) 4249453..4250742 + 1290 WP_235165541.1 MFS transporter -
NFI80_RS17580 (NFI80_17580) 4250823..4251257 + 435 WP_233794780.1 DoxX family protein -
NFI80_RS17585 (NFI80_17585) 4251261..4252136 - 876 WP_026629464.1 AraC family transcriptional regulator -
NFI80_RS17590 (NFI80_17590) 4252274..4252624 - 351 WP_235161189.1 RNA polymerase subunit sigma-24 -
NFI80_RS17595 (NFI80_17595) 4252656..4253627 - 972 WP_235165542.1 dihydrodipicolinate synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(5-127)

Antitoxin

Domain of unknown function DUF2281

(5-68)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14482.81 Da        Isoelectric Point: 4.6005

>T248104 WP_235165538.1 NZ_CP098805:4248258-4248641 [Dyadobacter chenhuakuii]
MNIILDTHALIWFFEGDSNLSAKALEAIENTNNKKFVSVASLWEIAIKTSLGKLTLQKPLDTFLSELVQSDIQILPISIN
QVLLVSQLDFFHKDPFDRIIIAQSITEKFPVVTKDPSFLLYPTDLYW

Download         Length: 384 bp

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8271.61 Da        Isoelectric Point: 4.5388

>AT248104 WP_235165537.1 NZ_CP098805:4248049-4248261 [Dyadobacter chenhuakuii]
MSEIELMNKMSVLPQNLREEVSDYVDFLISKYLHKDSLKKTPLKFGMMKGTFTMSPDFDEPLDDFKEYMP

Download         Length: 213 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References